OBJECTIVE: This study aimed to investigate the relation between alcohol consumption and type 2 diabetes among older women. RESEARCH DESIGN AND METHODS: Between 1993 and 1997, 16,330 women aged 49-70 years and free from diabetes were enrolled in one of the Dutch Prospect-EPIC (European Prospective Study Into Cancer and Nutrition) cohorts and followed for 6.2 years (range 0.1-10.1). At enrollment, women filled in questionnaires and blood samples were collected. RESULTS: During follow-up, 760 cases of type 2 diabetes were documented. A linear inverse association (P = 0.007) between alcohol consumption and type 2 diabetes risk was observed, adjusting for potential confounders. Compared with abstainers, the hazard ratio for type 2 diabetes was 0.86 (95% CI 0.66-1.12) for women consuming 5-30 g alcohol per week, 0.66 (0.48-0.91) for 30-70 g per week, 0.91 (0.67-1.24) for 70-140 g per week, 0.64 (0.44-0.93) for 140-210 g per week, and 0.69 (0.47-1.02) for >210 g alcohol per week. Beverage type did not influence this association. Lifetime alcohol consumption was associated with type 2 diabetes in a U-shaped fashion. CONCLUSIONS: Our findings support the evidence of a decreased risk of type 2 diabetes with moderate alcohol consumption and expand this to a population of older women.
OBJECTIVE: This study aimed to investigate the relation between alcohol consumption and type 2 diabetes among older women. RESEARCH DESIGN AND METHODS: Between 1993 and 1997, 16,330 women aged 49-70 years and free from diabetes were enrolled in one of the Dutch Prospect-EPIC (European Prospective Study Into Cancer and Nutrition) cohorts and followed for 6.2 years (range 0.1-10.1). At enrollment, women filled in questionnaires and blood samples were collected. RESULTS: During follow-up, 760 cases of type 2 diabetes were documented. A linear inverse association (P = 0.007) between alcohol consumption and type 2 diabetes risk was observed, adjusting for potential confounders. Compared with abstainers, the hazard ratio for type 2 diabetes was 0.86 (95% CI 0.66-1.12) for women consuming 5-30 g alcohol per week, 0.66 (0.48-0.91) for 30-70 g per week, 0.91 (0.67-1.24) for 70-140 g per week, 0.64 (0.44-0.93) for 140-210 g per week, and 0.69 (0.47-1.02) for >210 g alcohol per week. Beverage type did not influence this association. Lifetime alcohol consumption was associated with type 2 diabetes in a U-shaped fashion. CONCLUSIONS: Our findings support the evidence of a decreased risk of type 2 diabetes with moderate alcohol consumption and expand this to a population of older women.
Authors: Jennifer A Nettleton; Lisa J Harnack; Carolyn G Scrafford; Pamela J Mink; Leila M Barraj; David R Jacobs Journal: J Nutr Date: 2006-12 Impact factor: 4.798
Authors: Randall E Brand; Julia B Greer; Eugene Zolotarevsky; Rhonda Brand; Hongyan Du; Diane Simeone; Anna Zisman; Addi Gorchow; Shih-Yuan Connie Lee; Hemant K Roy; Michelle A Anderson Journal: Clin Gastroenterol Hepatol Date: 2009-06-26 Impact factor: 11.382
Authors: S van Dieren; C S P M Uiterwaal; Y T van der Schouw; D L van der A; J M A Boer; A Spijkerman; D E Grobbee; J W J Beulens Journal: Diabetologia Date: 2009-09-01 Impact factor: 10.122
Authors: F Bonnet; E Disse; M Laville; A Mari; K Hojlund; C H Anderwald; P Piatti; B Balkau Journal: Diabetologia Date: 2012-08-31 Impact factor: 10.122
Authors: Clara C Elbers; Carolien G F de Kovel; Yvonne T van der Schouw; Juliaan R Meijboom; Florianne Bauer; Diederick E Grobbee; Gosia Trynka; Jana V van Vliet-Ostaptchouk; Cisca Wijmenga; N Charlotte Onland-Moret Journal: PLoS One Date: 2009-09-17 Impact factor: 3.240
Authors: Dolly O Baliunas; Benjamin J Taylor; Hyacinth Irving; Michael Roerecke; Jayadeep Patra; Satya Mohapatra; Jürgen Rehm Journal: Diabetes Care Date: 2009-11 Impact factor: 17.152