Literature DB >> 16305872

Vacuum-assisted wound closure of deep sternal infections in high-risk patients after cardiac surgery.

Kyle Northcote Cowan1, Laura Teague, Sammy C Sue, James L Mahoney.   

Abstract

BACKGROUND: Sternal wound infections are a serious complication arising from cardiac surgery. Recently, the general application of negative pressure to wounds by vacuum-assisted closure (VAC) therapy has shown enhanced granulation and wound contraction. Here we examine the effect of VAC on sternal wounds.
METHODS: We collected and statistically analyzed quantitative VAC performance data and outcomes with a retrospective review on a consecutive cohort of 22 patients treated with VAC for post-cardiac surgery wound complications.
RESULTS: Sternal wound infections became evident on average at 21.0 days after surgery, associated with dehiscence (82%), sternal instability (59%), fluid collection by computed tomography (73%), and osteomyelitis (41%). Cultures most commonly identified Staphylococcus aureus (50%). Prompt irrigation and debridement were performed on all patients, and VAC therapy was applied at approximately 7.3 days after diagnosis. Vacuum-assisted closure induced granulation of 71% of the sternal wound area by 7 days, with a daily drainage of approximately 84 mL. By 14 days, there was a 54% reduction in wound size, and patients were discharged after approximately 19.5 days and placed on home therapy. Vacuum-assisted closure was discontinued at approximately 36.7 days with an average reduction in sternal wound size of 80%. Extensive secondary surgical closure, requiring muscle flaps, was avoided in 64% of patients, whereas 28% of patients required no surgical reconstruction for wound closure. No complications were related to VAC use.
CONCLUSIONS: In contrast to our earlier studies, adjunctive VAC therapy markedly reduced required surgical interventions, reoperation for persistent infections, and the hospitalization period. Thus, VAC provides a viable and efficacious adjunctive method by which to treat postoperative wound infection after medial sternotomy.

Entities:  

Mesh:

Year:  2005        PMID: 16305872     DOI: 10.1016/j.athoracsur.2005.04.005

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  19 in total

1.  The effectiveness of negative pressure therapy on infected wounds: preliminary results.

Authors:  Federico Lo Torto; Marco Ruggiero; Paola Parisi; Zachary Borab; Manuel Sergi; Bruno Carlesimo
Journal:  Int Wound J       Date:  2017-02-15       Impact factor: 3.315

Review 2.  Topical negative pressure wound therapy: a review of its role and guidelines for its use in the management of acute wounds.

Authors:  Estas Bovill; Paul E Banwell; Luc Teot; Elof Eriksson; Colin Song; Jim Mahoney; Ronny Gustafsson; Raymund Horch; Anand Deva; Ian Whitworth
Journal:  Int Wound J       Date:  2008-09-19       Impact factor: 3.315

3.  Evaluation of risk factors for hospital mortality and current treatment for poststernotomy mediastinitis.

Authors:  Akimasa Morisaki; Mitsuharu Hosono; Yasuyuki Sasaki; Hidekazu Hirai; Masanori Sakaguchi; Atsushi Nakahira; Hiroyuki Seo; Shigefumi Suehiro; Toshihiko Shibata
Journal:  Gen Thorac Cardiovasc Surg       Date:  2011-04-12

4.  Is post-sternotomy mediastinitis still devastating after the advent of negative-pressure wound therapy?

Authors:  Marisa De Feo; Alessandro Della Corte; Mariano Vicchio; Francesco Pirozzi; Gianantonio Nappi; Maurizio Cotrufo
Journal:  Tex Heart Inst J       Date:  2011

5.  Surgical options to treat massive sternal defect after failed Robicsek procedure.

Authors:  Andrea Dell'Amore; Alessio Campisi; Domenica Giunta; Stefano Congiu; Giampiero Dolci; Giacomo Murana; Sofia Martin Suarez; Niccolò Daddi
Journal:  J Thorac Dis       Date:  2018-06       Impact factor: 2.895

6.  Comparison of vacuum-assisted closure device and conservative treatment for fasciotomy wound healing in ischaemia-reperfusion syndrome: preliminary results.

Authors:  Karaca Saziye; Cikirikcioglu Mustafa; Uckay Ilker; Kalangos Afksendyios
Journal:  Int Wound J       Date:  2011-03-15       Impact factor: 3.315

Review 7.  Clinical outcome of diabetic foot ulcers treated with negative pressure wound therapy and the transition from acute care to home care.

Authors:  Stephanie C Wu; David G Armstrong
Journal:  Int Wound J       Date:  2008-06       Impact factor: 3.315

8.  Effects of negative pressure wound therapy on healing of free full-thickness skin grafts in dogs.

Authors:  Bryden J Stanley; Kathryn A Pitt; Christian D Weder; Michele C Fritz; Joe G Hauptman; Barbara A Steficek
Journal:  Vet Surg       Date:  2013-03-29       Impact factor: 1.495

9.  Topical negative pressure effects on coronary blood flow in a sternal wound model.

Authors:  Sandra Lindstedt; Malin Malmsjö; Bodil Gesslein; Richard Ingemansson
Journal:  Int Wound J       Date:  2008-10       Impact factor: 3.315

10.  Poststernotomy aspergillosis: successful treatment with voriconazole, surgical debridement and vacuum-assisted closure therapy.

Authors:  Rinaldo Focaccia Siciliano; Daniel Reis Waisberg; Marcos Naoyuki Samano; Paulo Ferreira Leite; Paulo Tuma Júnior; Guilherme Cardinali Barreiro; Tania Mara Varejão Strabelli
Journal:  Clinics (Sao Paulo)       Date:  2012       Impact factor: 2.365

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