Literature DB >> 16305686

HLA analysis of the Parsi (Zoroastrian) population in Pakistan.

A Mohyuddin1, S Q Mehdi.   

Abstract

The Parsis of Pakistan are descendants of Zoroastrians from Iran who fled to Gujarat in India after the Arab invasion in 900 AD. A small group eventually migrated from India to Karachi in Pakistan. In this study, the Parsis from Pakistan were analyzed at the HLA-B, -C, -DRB1 and -DQB1 loci using the polymerase chain reaction with sequence-specific primers (PCR-SSP). The most common alleles at the HLA loci were HLA-B*35 (15.9%), HLA-Cw*0602 (21.4%), HLA-DRB1*11 (23.0%), and HLA-DQB1*02 (24.7%). Data analysis suggests that the Parsis of Pakistan and India descended from the same stock and may have the closest ancestry with Jewish and Italian populations.

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Year:  2005        PMID： 16305686     DOI： 10.1111/j.1399-0039.2005.00507.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN： 0001-2815


  4 in total

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3.  The Genetic Legacy of Zoroastrianism in Iran and India: Insights into Population Structure, Gene Flow, and Selection.

Authors:  Saioa López; Mark G Thomas; Lucy van Dorp; Naser Ansari-Pour; Sarah Stewart; Abigail L Jones; Erik Jelinek; Lounès Chikhi; Tudor Parfitt; Neil Bradman; Michael E Weale; Garrett Hellenthal
Journal:  Am J Hum Genet       Date:  2017-08-24       Impact factor: 11.025

4.  "Like sugar in milk": reconstructing the genetic history of the Parsi population.

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Journal:  Genome Biol       Date:  2017-06-14       Impact factor: 13.583
  4 in total

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