Literature DB >> 16304401

MGUS and smoldering multiple myeloma: update on pathogenesis, natural history, and management.

S Vincent Rajkumar1.   

Abstract

Monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) are asymptomatic, pre-malignant disorders characterized by monoclonal plasma cell proliferation in the bone marrow and absence of end-organ damage. Recent advances in the pathogenesis, natural history, and prognosis of MGUS and SMM are reviewed. A new risk stratification system to determine the prognosis of MGUS using the size and type of M protein, and the serum free light chain assay is discussed.

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Year:  2005        PMID： 16304401     DOI： 10.1182/asheducation-2005.1.340

Source DB:  PubMed          Journal:  Hematology Am Soc Hematol Educ Program        ISSN： 1520-4383


  23 in total

1.  Incidental finding of monoclonal gammopathy in blood donors: a follow-up study.

Authors:  Massimo La Raja; Monica Barcobello; Nicola Bet; Paolo Dolfini; Marina Florean; Federica Tomasella; Vincenzo De Angelis; Luca Mascaretti
Journal:  Blood Transfus       Date:  2012-03-28       Impact factor: 3.443

2.  Genomic analysis of high-risk smoldering multiple myeloma.

Authors:  Lucía López-Corral; María Victoria Mateos; Luis A Corchete; María Eugenia Sarasquete; Javier de la Rubia; Felipe de Arriba; Juan-José Lahuerta; Ramón García-Sanz; Jesús F San Miguel; Norma C Gutiérrez
Journal:  Haematologica       Date:  2012-02-13       Impact factor: 9.941

Review 3.  Multiple myeloma.

Authors:  S Vincent Rajkumar
Journal:  Curr Probl Cancer       Date:  2009 Jan-Feb       Impact factor: 3.187

4.  Incidence, clinical course, and prognosis of secondary monoclonal gammopathy of undetermined significance in patients with multiple myeloma.

Authors:  Rishi K Wadhera; Robert A Kyle; Dirk R Larson; Angela Dispenzieri; Shaji Kumar; Hillard M Lazarus; S Vincent Rajkumar
Journal:  Blood       Date:  2011-07-15       Impact factor: 22.113

5.  Risk factors for monoclonal gammopathy of undetermined significance: a systematic review.

Authors:  Maira A Castaneda-Avila; Christine M Ulbricht; Mara Meyer Epstein
Journal:  Ann Hematol       Date:  2021-01-08       Impact factor: 3.673

6.  The ubiquitin-proteasomal system is critical for multiple myeloma: implications in drug discovery.

Authors:  Biyin Cao; Xinliang Mao
Journal:  Am J Blood Res       Date:  2011-05-25

Review 7.  Clinical Relevance of Multicolour Flow Cytometry in Plasma Cell Disorders.

Authors:  Gaurav Chatterjee; Sumeet Gujral; Papagudi G Subramanian; Prashant R Tembhare
Journal:  Indian J Hematol Blood Transfus       Date:  2017-04-26       Impact factor: 0.900

8.  Risk of plasma cell and lymphoproliferative disorders among 14621 first-degree relatives of 4458 patients with monoclonal gammopathy of undetermined significance in Sweden.

Authors:  Ola Landgren; Sigurdur Y Kristinsson; Lynn R Goldin; Neil E Caporaso; Cecilie Blimark; Ulf-Henrik Mellqvist; Anders Wahlin; Magnus Bjorkholm; Ingemar Turesson
Journal:  Blood       Date:  2009-01-30       Impact factor: 22.113

Review 9.  Autoimmunity and lymphomagenesis.

Authors:  Lynn R Goldin; Ola Landgren
Journal:  Int J Cancer       Date:  2009-04-01       Impact factor: 7.396

10.  Cancer incidence among pesticide applicators exposed to permethrin in the Agricultural Health Study.

Authors:  Jennifer A Rusiecki; Rahulkumar Patel; Stella Koutros; Laura Beane-Freeman; Ola Landgren; Matthew R Bonner; Joseph Coble; Jay Lubin; Aaron Blair; Jane A Hoppin; Michael C R Alavanja
Journal:  Environ Health Perspect       Date:  2008-11-10       Impact factor: 9.031
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