Literature DB >> 16304336

An in vitro evaluation of the effectiveness of endotracheal suction catheters.

Samir Shah1, Kevin Fung, Sandy Brim, Bruce K Rubin.   

Abstract

INTRODUCTION: Tracheal suction catheters (TSCs) are used to clear mucus from an endotracheal tube (ETT). The clearance rate is critical because airway mucus stasis leads to obstruction, but prolonged catheter suctioning can lead to hypoxemia. The rate of mucus clearance from an ETT is thought to be influenced by the properties of the mucus, the pressure used to suction the mucus, and the diameter of the catheter. In this study, different adult TSCs were evaluated for their ability to suction mucus simulants that had properties similar to airway mucus.
METHODS: Six different 14F TSC designs were evaluated. All catheters had the same end hole size, but the two side holes were sized at 3 mm, 4 mm, or 5 mm. A coagulant (Polyox Water Soluble Resin Coagulant NF; Dow Chemical Company; Cary, NC) was mixed with water at concentrations of 0.5%, 1.5%, and 3.0% to simulate mucus or sputum. Suction effectiveness was evaluated by the mass percentage of the coagulant suctioned over 10 s at 100 mm Hg from an 8.0 ETT. MEASUREMENTS AND
RESULTS: The 1.5% and 3.0% simulants had properties comparable to human airway mucus and sputum. Suction effectiveness was less with the 3.0% coagulant simulant compared with the 1.5% and 0.5% simulants. Suction effectiveness was greater (p < 0.01) with TSCs that had nonparallel holes and a side hole diameter of 5 mm when tested with the 1.5% and 3.0% simulants. However, no best catheter could be identified among TSCs when tested with the more liquid-like 0.5% simulant.
CONCLUSIONS: Greater TSC side hole diameter and nonparallel positioning was important for suctioning mucus simulants that are similar to mucus or sputum. The distance between side holes, end hole size, suction force, and duration of suctioning were not tested but could also have an effect on TSC performance.

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Mesh:

Year:  2005        PMID: 16304336     DOI: 10.1378/chest.128.5.3699

Source DB:  PubMed          Journal:  Chest        ISSN: 0012-3692            Impact factor:   9.410


  7 in total

1.  A novel visual sputum suctioning system is useful for endotracheal suctioning in a dog model.

Authors:  Xun Liu; Huisheng Deng; Ziyang Huang; Bingbing Yan; Jingjing Lv; Jinxing Wu
Journal:  Int J Clin Exp Med       Date:  2014-12-15

2.  Effects of intrapulmonary percussive ventilation on airway mucus clearance: A bench model.

Authors:  Lorena Fernandez-Restrepo; Lauren Shaffer; Bravein Amalakuhan; Marcos I Restrepo; Jay Peters; Ruben Restrepo
Journal:  World J Crit Care Med       Date:  2017-08-04

3.  Effects of manual hyperinflation, clinical practice versus expert recommendation, on displacement of mucus simulant: A laboratory study.

Authors:  Marcia S Volpe; Juliane M Naves; Gabriel G Ribeiro; Gualberto Ruas; Mauro R Tucci
Journal:  PLoS One       Date:  2018-02-12       Impact factor: 3.240

4.  A STELLA simulation model for in vitro dissolution testing of respirable size particles.

Authors:  Basanth Babu Eedara; Ian G Tucker; Shyamal C Das
Journal:  Sci Rep       Date:  2019-12-06       Impact factor: 4.379

5.  Evaluation of a novel endotracheal tube suctioning system incorporating an inflatable sweeper.

Authors:  John D Davies; Yuh Chin Huang; Neil R MacIntyre
Journal:  Can J Respir Ther       Date:  2021-10-12

Review 6.  Mucus Clearance Strategies in Mechanically Ventilated Patients.

Authors:  Ryan L Goetz; Kadambari Vijaykumar; George M Solomon
Journal:  Front Physiol       Date:  2022-03-23       Impact factor: 4.566

7.  Use of PBPK Modeling To Evaluate the Performance of Dissolv It, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products.

Authors:  Mireille Hassoun; Maria Malmlöf; Otto Scheibelhofer; Abhinav Kumar; Sukhi Bansal; Ewa Selg; Mattias Nowenwik; Per Gerde; Snezana Radivojev; Amrit Paudel; Sumit Arora; Ben Forbes
Journal:  Mol Pharm       Date:  2019-02-15       Impact factor: 4.939

  7 in total

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