Literature DB >> 16303068

Recurrent bacterial vaginosis: the use of maintenance acidic vaginal gel following treatment.

J D Wilson1, S M Shann, S K Brady, A G Mammen-Tobin, A L Evans, R A Lee.   

Abstract

Bacterial vaginosis (BV) frequently recurs after treatment. One option in the management of recurrences is to keep the vaginal pH at 4.5 or less, in order to prevent overgrowth of bacteria, until the normal lactobacilli are re-established. We report the outcome of using maintenance acetic acid vaginal gel, after treatment of BV, in a sample of 49 women with frequent recurrences. Half of the women had no further recurrences, and in those who did there was a significant increase in time to first recurrence (4.8 months) after commencing the gel compared with the previous recurrence (2.1 months). Prior to using acidic gel, the mean recurrence rate in 49 women was 4.4 per woman/year, and this was reduced to 0.6 recurrences per woman/year. As there are few effective therapies for women with recurrent BV, we feel this offers an option that can currently be used in clinical practice.

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Year:  2005        PMID: 16303068     DOI: 10.1258/095646205774763081

Source DB:  PubMed          Journal:  Int J STD AIDS        ISSN: 0956-4624            Impact factor:   1.359


  5 in total

1.  Findings associated with recurrence of bacterial vaginosis among adolescents attending sexually transmitted diseases clinics.

Authors:  Rebecca M Brotman; Emily J Erbelding; Roxanne M Jamshidi; Mark A Klebanoff; Jonathan M Zenilman; Khalil G Ghanem
Journal:  J Pediatr Adolesc Gynecol       Date:  2007-08       Impact factor: 1.814

Review 2.  Vaginal discharge.

Authors:  Des Spence; Catriona Melville
Journal:  BMJ       Date:  2007-12-01

3.  Topical penile microbicide use by men to prevent recurrent bacterial vaginosis in sex partners: a randomized clinical trial.

Authors:  Elizabeth Bukusi; Katherine K Thomas; Rosemary Nguti; Craig R Cohen; Noel Weiss; Robert W Coombs; King K Holmes
Journal:  Sex Transm Dis       Date:  2011-06       Impact factor: 2.830

4.  Extended antimicrobial treatment of bacterial vaginosis combined with human lactobacilli to find the best treatment and minimize the risk of relapses.

Authors:  Per-Göran Larsson; Erik Brandsborg; Urban Forsum; Sonal Pendharkar; Kasper Krogh Andersen; Salmir Nasic; Lennart Hammarström; Harold Marcotte
Journal:  BMC Infect Dis       Date:  2011-08-19       Impact factor: 3.090

5.  Antibacterial treatment of bacterial vaginosis: current and emerging therapies.

Authors:  Jean-Pierre Menard
Journal:  Int J Womens Health       Date:  2011-08-23
  5 in total

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