Literature DB >> 1630306

Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G+C-content biases.

K Tamura1.   

Abstract

A simple mathematical method is developed to estimate the number of nucleotide substitutions per site between two DNA sequences, by extending Kimura's (1980) two-parameter method to the case where a G+C-content bias exists. This method will be useful when there are strong transition-transversion and G+C-content biases, as in the case of Drosophila mitochondrial DNA.

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Year:  1992        PMID： 1630306     DOI： 10.1093/oxfordjournals.molbev.a040752

Source DB:  PubMed          Journal:  Mol Biol Evol        ISSN： 0737-4038            Impact factor:   16.240


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