Literature DB >> 16302726

Multiple roles of cyclooxygenase-2 in endometrial cancer.

Satoshi Ohno1, Yumiko Ohno, Nobutaka Suzuki, Hiroyuki Inagawa, Chie Kohchi, Gen-Ichiro Soma, Masaki Inoue.   

Abstract

Cyclooxygenase-2 (COX-2) plays a critical role not only in maintenance of the endometrium during the menstrual cycle, but also in the progression of endometrial cancer. The role of COX-2 in tumor growth and development is complex and multifaceted. This review presents evidence for the expression of COX-2 being linked to angiogenesis, tumor cell apoptosis, tumor cell growth, metastasis and local immunosuppression in cancer progression. It also outlines the clinicopathological and prognostic significance of COX-2 in endometrial cancer.

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Year:  2005        PMID： 16302726

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  12 in total

1.  Polymorphisms in cyclooxygenase-2 gene in endometrial cancer patients.

Authors:  Federica Torricelli; Vincenzo Dario Mandato; Enrico Farnetti; Martino Abrate; Bruno Casali; Gino Ciarlini; Debora Pirillo; Maria Carolina Gelli; Luigi Costagliola; Davide Nicoli; Stefano Palomba; Giovanni Battista La Sala
Journal:  Tumour Biol       Date:  2015-04-22

2.  Oxytocin increases invasive properties of endometrial cancer cells through phosphatidylinositol 3-kinase/AKT-dependent up-regulation of cyclooxygenase-1, -2, and X-linked inhibitor of apoptosis protein.

Authors:  Marie-Claude Déry; Parvesh Chaudhry; Valérie Leblanc; Sophie Parent; Anne-Marie Fortier; Eric Asselin
Journal:  Biol Reprod       Date:  2011-08-03       Impact factor: 4.285

3.  Prognostic Impact of ABO Blood Group on Type I Endometrial Cancer Patients- Results from Our Own and Other Studies.

Authors:  Vincenzo Dario Mandato; Federica Torricelli; Valentina Mastrofilippo; Gino Ciarlini; Debora Pirillo; Enrico Farnetti; Loretta Fornaciari; Bruno Casali; Maria Carolina Gelli; Martino Abrate; Lorenzo Aguzzoli; Giovanni Battista La Sala; Davide Nicoli
Journal:  J Cancer       Date:  2017-08-23       Impact factor: 4.207

4.  Cyclooxygenase-2 gene and epithelial ovarian carcinoma risk.

Authors:  Bedia Agachan Cakmakoglu; Rukset Attar; Ozlem Timirci Kahraman; Altay Burak Dalan; Ahmet Cem Iyibozkurt; Ates Karateke; Erkut Attar
Journal:  Mol Biol Rep       Date:  2010-11-24       Impact factor: 2.316

Review 5.  Immunotherapy in endometrial cancer: rationale, practice and perspectives.

Authors:  Wenyu Cao; Xinyue Ma; Jean Victoria Fischer; Chenggong Sun; Beihua Kong; Qing Zhang
Journal:  Biomark Res       Date:  2021-06-16

6.  Co-expression of survivin, c-erbB2, and cyclooxygenase-2 (COX-2): prognostic value and survival of endometrial cancer patients.

Authors:  Maria Lambropoulou; Nikolaos Papadopoulos; Grigoris Tripsianis; George Alexiadis; Olga Pagonopoulou; Anastasia Kiziridou; Vassilios Liberis; Stylianos Kakolyris; Ekaterini Chatzaki
Journal:  J Cancer Res Clin Oncol       Date:  2009-09-16       Impact factor: 4.553

7.  COX-2 (PTGS2) gene methylation in epithelial, subepithelial lymphocyte and stromal tissue compartments in a spectrum of esophageal squamous neoplasia.

Authors:  Sonja P Dawsey; Mark J Roth; Lisa Adams; Nan Hu; Quan-Hong Wang; Philip R Taylor; Karen Woodson
Journal:  Cancer Detect Prev       Date:  2008-07-16

8.  Is ABO blood group a risk or prognostic factor for patients with endometrioid endometrial cancer? A retrospective analysis in Germany.

Authors:  Georgios Gitas; Louisa Proppe; Ibrahim Alkatout; Dimitrios Tsolakidis; Achim Rody; Christos Kotanidis; Sascha Baum
Journal:  Blood Transfus       Date:  2020-06-04       Impact factor: 3.443

Review 9.  Emerging therapeutic biomarkers in endometrial cancer.

Authors:  Peixin Dong; Masanori Kaneuchi; Yosuke Konno; Hidemichi Watari; Satoko Sudo; Noriaki Sakuragi
Journal:  Biomed Res Int       Date:  2013-06-11       Impact factor: 3.411

10.  Effects of ectopic HER-2/neu gene expression on the COX-2/PGE2/P450arom signaling pathway in endometrial carcinoma cells: HER-2/neu gene expression in endometrial carcinoma cells.

Authors:  Shu Li; XiaoXin Ma; Li Ma; Cuicui Wang; YuanQi He; ZhiJuan Yu
Journal:  J Exp Clin Cancer Res       Date:  2013-03-02
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