Literature DB >> 16301496

Lack of association between VEGF polymorphisms and ALS in a Dutch population.

P W J Van Vught1, N A Sutedja, J H Veldink, B P C Koeleman, G J Groeneveld, C Wijmenga, B M J Uitdehaag, J M B V de Jong, F Baas, J H J Wokke, L H Van den Berg.   

Abstract

Sequence alterations in the promoter region of the vascular endothelial growth factor (VEGF) gene have been implicated in increasing the risk of developing ALS. VEGF promoter haplotypes were determined in 373 patients with sporadic ALS and 615 matched healthy controls in The Netherlands. No significant association between the previously reported at-risk haplotypes and ALS was found. Pooling our results with the previously studied population still showed a significant association with the AAG haplotype.

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Year:  2005        PMID： 16301496     DOI： 10.1212/01.wnl.0000184514.39853.56

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  10 in total

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Authors:  Yubin Wu; Yingying Zhang; Xun Han; Xiaoyuan Li; Li Xue; Anmu Xie
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9.  Screening of the transcriptional regulatory regions of vascular endothelial growth factor receptor 2 (VEGFR2) in amyotrophic lateral sclerosis.

Authors:  Alice Brockington; Beatrijs Wokke; Hannah Nixon; Judith Hartley; Pamela J Shaw
Journal:  BMC Med Genet       Date:  2007-04-24       Impact factor: 2.103

Review 10.  ALS and oxidative stress: the neurovascular scenario.

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Journal:  Oxid Med Cell Longev       Date:  2013-12-03       Impact factor: 6.543
  10 in total

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