Literature DB >> 16301449

Autoimmune pancreatitis: unveiling a hidden entity.

Michael Wayne1, Keith A Delman, Tolga Kurt, Robert Grossi, Maria Sabatini, Avram Cooperman.   

Abstract

HYPOTHESIS: After alcohol-induced and hereditary disease, idiopathic chronic pancreatitis is the most common cause of calcifying pancreatitis. This designation is used when no associated cause of chronic pancreatitis is found. We present 6 cases of idiopathic pancreatitis in which the postoperative pathological examination results demonstrated lymphoplasmacytic sclerosing pancreatitis or autoimmune pancreatitis.
DESIGN: Retrospective case series. The medical records of 6 patients referred and treated for autoimmune pancreatitis were reviewed. The duration of follow-up varies, the longest being 5 years. The disease and a literature review are reported.
SETTING: A 200-bed community hospital located in a large city. The patients were referred after being treated elsewhere for recurrent pancreatitis. PATIENTS AND METHODS: Six patients with chronic recurrent pancreatitis were evaluated. They were selected because pathological review indicated that they all had autoimmune pancreatitis.
RESULTS: Six cases of lymphoplasmacytic sclerosing pancreatitis are presented and suggest that lymphoplasmacytic sclerosing pancreatitis should be thought of more often in chronic autoimmune pancreatitis.
CONCLUSION: Lymphoplasmacytic sclerosing pancreatitis is an increasingly recognized cause of chronic pancreatitis and should be considered in the evaluation of patients with chronic pancreatitis and no discernible cause.

Entities:  

Mesh:

Year:  2005        PMID: 16301449     DOI: 10.1001/archsurg.140.11.1104

Source DB:  PubMed          Journal:  Arch Surg        ISSN: 0004-0010


  2 in total

1.  Clinical and radiologic resolution of IgG 4 normal, nonoperatively diagnosed lymphoplasmacytic sclerosing pancreatitis (LPSP) after initiation of steroid therapy.

Authors:  Stephen W Behrman; Shamim M Moinuddin; Donald S Gravenor
Journal:  J Gastrointest Surg       Date:  2007-09       Impact factor: 3.452

Review 2.  Acute recurrent pancreatitis: an autoimmune disease?

Authors:  Raffaele Pezzilli
Journal:  World J Gastroenterol       Date:  2008-02-21       Impact factor: 5.742

  2 in total

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