Literature DB >> 16299345

Attenuation of Salmonella enterica Serovar Typhimurium by altering biological functions of murein lipoprotein and lipopolysaccharide.

A A Fadl1, J Sha, G R Klimpel, J P Olano, C L Galindo, A K Chopra.   

Abstract

We constructed Salmonella enterica serovar Typhimurium double-knockout mutants in which either the lipoprotein A (lppA) or the lipoprotein B (lppB) gene was deleted from an msbB-negative background strain by marker exchange mutagenesis. These mutants were highly attenuated when tested with in vitro and in vivo models of Salmonella pathogenesis.

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Year:  2005        PMID： 16299345      PMCID： PMC1307095          DOI： 10.1128/IAI.73.12.8433-8436.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  9 in total

1.  Murein lipoprotein is a critical outer membrane component involved in Salmonella enterica serovar typhimurium systemic infection.

Authors:  A A Fadl; J Sha; G R Klimpel; J P Olano; D W Niesel; A K Chopra
Journal:  Infect Immun       Date:  2005-02       Impact factor: 3.441

2.  Extragenic suppressors of growth defects in msbB Salmonella.

Authors:  S R Murray; D Bermudes; K S de Felipe; K B Low
Journal:  J Bacteriol       Date:  2001-10       Impact factor: 3.490

3.  Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB.

Authors:  T Clementz; Z Zhou; C R Raetz
Journal:  J Biol Chem       Date:  1997-04-18       Impact factor: 5.157

4.  Mutation of the htrB gene in a virulent Salmonella typhimurium strain by intergeneric transduction: strain construction and phenotypic characterization.

Authors:  M G Sunshine; B W Gibson; J J Engstrom; W A Nichols; B D Jones; M A Apicella
Journal:  J Bacteriol       Date:  1997-09       Impact factor: 3.490

5.  Bacterial lipoprotein and lipopolysaccharide act synergistically to induce lethal shock and proinflammatory cytokine production.

Authors:  H Zhang; J W Peterson; D W Niesel; G R Klimpel
Journal:  J Immunol       Date:  1997-11-15       Impact factor: 5.422

6.  Lipid A mutant Salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivo.

Authors:  K B Low; M Ittensohn; T Le; J Platt; S Sodi; M Amoss; O Ash; E Carmichael; A Chakraborty; J Fischer; S L Lin; X Luo; S I Miller; L Zheng; I King; J M Pawelek; D Bermudes
Journal:  Nat Biotechnol       Date:  1999-01       Impact factor: 54.908

7.  A novel Escherichia coli lipid A mutant that produces an antiinflammatory lipopolysaccharide.

Authors:  J E Somerville; L Cassiano; B Bainbridge; M D Cunningham; R P Darveau
Journal:  J Clin Invest       Date:  1996-01-15       Impact factor: 14.808

8.  Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide.

Authors:  C C Schuerer-Maly; L Eckmann; M F Kagnoff; M T Falco; F E Maly
Journal:  Immunology       Date:  1994-01       Impact factor: 7.397

9.  The two murein lipoproteins of Salmonella enterica serovar Typhimurium contribute to the virulence of the organism.

Authors:  J Sha; A A Fadl; G R Klimpel; D W Niesel; V L Popov; A K Chopra
Journal:  Infect Immun       Date:  2004-07       Impact factor: 3.441
  9 in total
  6 in total

1.  Deletion of the Braun lipoprotein-encoding gene and altering the function of lipopolysaccharide attenuate the plague bacterium.

Authors:  Jian Sha; Michelle L Kirtley; Christina J van Lier; Shaofei Wang; Tatiana E Erova; Elena V Kozlova; Anthony Cao; Yingzi Cong; Eric C Fitts; Jason A Rosenzweig; Ashok K Chopra
Journal:  Infect Immun       Date:  2012-12-28       Impact factor: 3.441

2.  Enterobacterial common antigen mutants of Salmonella enterica serovar Typhimurium establish a persistent infection and provide protection against subsequent lethal challenge.

Authors:  Jeremy J Gilbreath; Jennifer Colvocoresses Dodds; Paul D Rick; Mark J Soloski; D Scott Merrell; Eleanor S Metcalf
Journal:  Infect Immun       Date:  2011-10-24       Impact factor: 3.441

3.  Immunological responses against Salmonella enterica serovar Typhimurium Braun lipoprotein and lipid A mutant strains in Swiss-Webster mice: potential use as live-attenuated vaccines.

Authors:  Tie Liu; Rolf König; Jian Sha; Stacy L Agar; Chien-Te K Tseng; Gary R Klimpel; Ashok K Chopra
Journal:  Microb Pathog       Date:  2007-10-06       Impact factor: 3.738

4.  Braun lipoprotein (Lpp) contributes to virulence of yersiniae: potential role of Lpp in inducing bubonic and pneumonic plague.

Authors:  Jian Sha; Stacy L Agar; Wallace B Baze; Juan P Olano; Amin A Fadl; Tatiana E Erova; Shaofei Wang; Sheri M Foltz; Giovanni Suarez; Vladimir L Motin; Sadhana Chauhan; Gary R Klimpel; Johnny W Peterson; Ashok K Chopra
Journal:  Infect Immun       Date:  2008-01-28       Impact factor: 3.441

5.  Protective Immunity Elicited by Oral Immunization of Mice with Salmonella enterica Serovar Typhimurium Braun Lipoprotein (Lpp) and Acetyltransferase (MsbB) Mutants.

Authors:  Tatiana E Erova; Michelle L Kirtley; Eric C Fitts; Duraisamy Ponnusamy; Wallace B Baze; Jourdan A Andersson; Yingzi Cong; Bethany L Tiner; Jian Sha; Ashok K Chopra
Journal:  Front Cell Infect Microbiol       Date:  2016-11-10       Impact factor: 5.293

6.  An enteric pathogen Salmonella enterica serovar Typhimurium suppresses tumor growth by downregulating CD44high and CD4T regulatory (Treg) cell expression in mice: the critical role of lipopolysaccharide and Braun lipoprotein in modulating tumor growth.

Authors:  T Liu; A K Chopra
Journal:  Cancer Gene Ther       Date:  2009-08-28       Impact factor: 5.987
  6 in total

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