Literature DB >> 16298783

Observation of the morphology and calcium content of vestibular otoconia in rats after simulated weightlessness.

Jiangping Zhang1, Zhenhui Peng, Miaoli Yang, Xianghong Zhang, Junrong Wei, Min Xu, Qing Yin Zheng.   

Abstract

Reduction in bone formation may have been the main reason for the lower calcium content of the otoconia after simulated weightlessness in rats. The head-ward distribution of blood volume may explain the morphological changes observed in the middle and inner ears. To observe morphological changes in the vestibular organs and measure the calcium content of otoconia in rats after simulated weightlessness. We used a tail suspension model of simulated weightlessness and then investigated changes in the vestibular organs using scanning electron microscopy and X-ray microanalysis. In comparison to untreated rats, the vestibular otoconia of the rats subjected to simulated weightlessness were small, irregularly shaped or fissured, and were arranged loosely and out of order. In addition, the calcium content of the otoconia was markedly decreased.

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Year:  2005        PMID: 16298783      PMCID: PMC2858292          DOI: 10.1080/00016480510037915

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  18 in total

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  4 in total

1.  Repeated exposure attenuates the behavioral response of rats to static high magnetic fields.

Authors:  Thomas A Houpt; Jennifer A Cassell; Alison Hood; Megan DenBleyker; Ilana Janowitz; Kathleen Mueller; Breyda Ortega; James C Smith
Journal:  Physiol Behav       Date:  2010-01-05

2.  Long-term behavioral effects observed in mice chronically exposed to static ultra-high magnetic fields.

Authors:  Ivan Tkáč; Michael A Benneyworth; Tessa Nichols-Meade; Elizabeth L Steuer; Sarah N Larson; Gregory J Metzger; Kâmil Uğurbil
Journal:  Magn Reson Med       Date:  2021-04-06       Impact factor: 4.668

3.  Otoconia Structure After Short- and Long-Duration Exposure to Altered Gravity.

Authors:  Richard Boyle; Joseph Varelas
Journal:  J Assoc Res Otolaryngol       Date:  2021-05-18

Review 4.  Challenges to the Vestibular System in Space: How the Brain Responds and Adapts to Microgravity.

Authors:  Jérome Carriot; Isabelle Mackrous; Kathleen E Cullen
Journal:  Front Neural Circuits       Date:  2021-11-03       Impact factor: 3.492

  4 in total

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