Literature DB >> 16297338

Molecular mechanisms regulating expression and function of transcription regulator inhibitor of differentiation 3.

Robert Wai-Sui Lim1, Jin-Mei Wu.   

Abstract

The transcription factor antagonist inhibitor of differentiation 3 (Id3) has been implicated in many diverse developmental, physiological and pathophysiological processes. Its expression and function is subjected to many levels of complex regulation. This review summarizes the current understanding of these mechanisms and describes how they might be related to the diverse functions that have been attributed to the Id3 protein. Detailed understanding of these mechanisms should provide insights towards the development of therapeutic approaches to various diseases, including cancer and atherogenesis.

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Year:  2005        PMID： 16297338     DOI： 10.1111/j.1745-7254.2005.00207.x

Source DB:  PubMed          Journal:  Acta Pharmacol Sin        ISSN： 1671-4083            Impact factor:   6.150


  8 in total

1.  Inhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansion.

Authors:  Alexis Cutchins; Daniel B Harmon; Jennifer L Kirby; Amanda C Doran; Stephanie N Oldham; Marcus Skaflen; Alexander L Klibanov; Nahum Meller; Susanna R Keller; James Garmey; Coleen A McNamara
Journal:  Arterioscler Thromb Vasc Biol       Date:  2011-11-10       Impact factor: 8.311

2.  The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma.

Authors:  Seung-Hee Lee; Ergeng Hao; Alice Kiselyuk; James Shapiro; David J Shields; Andrew Lowy; Fred Levine; Pamela Itkin-Ansari
Journal:  Mol Cancer Res       Date:  2011-04-15       Impact factor: 5.852

3.  Overexpression of Id3 induces apoptosis of A549 human lung adenocarcinoma cells.

Authors:  X-J Li; C-D Zhu; W Yu; P Wang; F-F Chen; X-Y Xia; B Luo
Journal:  Cell Prolif       Date:  2011-12-07       Impact factor: 6.831

4.  Effects of upregulation of Id3 in human lung adenocarcinoma cells on proliferation, apoptosis, mobility and tumorigenicity.

Authors:  F-F Chen; Y Liu; F Wang; X-J Pang; C-D Zhu; M Xu; W Yu; X-J Li
Journal:  Cancer Gene Ther       Date:  2015-09-18       Impact factor: 5.987

5.  Cross talk between Id1 and its interactive protein Dril1 mediate fibroblast responses to transforming growth factor-beta in pulmonary fibrosis.

Authors:  Ling Lin; Zhihong Zhou; Liang Zheng; Sean Alber; Simon Watkins; Prabir Ray; Naftali Kaminski; Yingze Zhang; Danielle Morse
Journal:  Am J Pathol       Date:  2008-06-26       Impact factor: 4.307

Review 6.  ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities.

Authors:  Radhika Nair; Wee Siang Teo; Vivek Mittal; Alexander Swarbrick
Journal:  Mol Ther       Date:  2014-05-14       Impact factor: 11.454

Review 7.  Contribution of Inhibitor of DNA Binding/Differentiation-3 and Endocrine Disrupting Chemicals to Pathophysiological Aspects of Chronic Disease.

Authors:  Vincent Avecilla; Mayur Doke; Quentin Felty
Journal:  Biomed Res Int       Date:  2017-07-13       Impact factor: 3.411

Review 8.  Point Mutation Specific Antibodies in B-Cell and T-Cell Lymphomas and Leukemias: Targeting IDH2, KRAS, BRAF and Other Biomarkers RHOA, IRF8, MYD88, ID3, NRAS, SF3B1 and EZH2.

Authors:  Kunwar Singh; Sumanth Gollapudi; Sasha Mittal; Corinn Small; Jyoti Kumar; Robert S Ohgami
Journal:  Diagnostics (Basel)       Date:  2021-03-27
  8 in total

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