Literature DB >> 16296800

Controlled inhalation of aerosolised therapeutics.

William D Bennett1.   

Abstract

With the advent of new, and often expensive, therapeutics designed for aerosol delivery to the lung, there is a need to improve the targeting and efficiency of their delivery. By controlling breathing patterns associated with inhaled aerosols, it has been shown that deposition in the lung can be both maximised and targeted to specific lung regions. A new commercially available device, the AKITA (Inamed GmbH) allows for individualised, controlled inhalation of aerosols produced by conventional nebulisers. Smart card technology is incorporated into the AKITA to both individualise breathing patterns as well as record compliance of therapy. So far, the use of this new device has provided maximal delivery of drug to the lung, with improved patient compliance and minimal waste of drug.

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Year:  2005        PMID: 16296800     DOI: 10.1517/17425247.2.4.763

Source DB:  PubMed          Journal:  Expert Opin Drug Deliv        ISSN: 1742-5247            Impact factor:   6.648


  4 in total

1.  The I-neb Adaptive Aerosol Delivery System enhances delivery of alpha1-antitrypsin with controlled inhalation.

Authors:  David E Geller; Kenneth C Kesser
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2010-04       Impact factor: 2.849

Review 2.  Are inhaled systemic therapies a viable option for the treatment of the elderly patient?

Authors:  Stephen Allen
Journal:  Drugs Aging       Date:  2008       Impact factor: 3.923

Review 3.  Prospects of Inhaled Phage Therapy for Combatting Pulmonary Infections.

Authors:  Xiang Wang; Zuozhou Xie; Jinhong Zhao; Zhenghua Zhu; Chen Yang; Yi Liu
Journal:  Front Cell Infect Microbiol       Date:  2021-12-06       Impact factor: 5.293

4.  Magnetic core-shell nanoparticles for drug delivery by nebulization.

Authors:  Navin Kumar Verma; Kieran Crosbie-Staunton; Amro Satti; Shane Gallagher; Katie B Ryan; Timothy Doody; Colm McAtamney; Ronan MacLoughlin; Paul Galvin; Conor S Burke; Yuri Volkov; Yurii K Gun'ko
Journal:  J Nanobiotechnology       Date:  2013-01-23       Impact factor: 10.435

  4 in total

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