Primary squamous cell carcinoma of gallbladder presenting as acute cholecystitis.

Primary squamous cell carcinoma of gallbladder accounts for only 0-12.7% of all cases of gallbladder cancer. We here report a case of primary squamous cell carcinoma of gallbladder presenting as acute cholecystitis. A 50 year old man was admitted with the complaints of pain in right hypochondrium and fever of 2 days duration. Abdominal examination revealed tenderness along with guarding and rigidity in right hypochondrium with positive Murphy's sign. The patient was conservatively treated as a case of acute cholecystitis. After 12 hrs of unrewarding treatment patient was operated upon and cholecystectomy done. The specimen revealed thick walled gallbladder with multiple calculi. Histopathology revealed squamous cell carcinoma grade II.