Literature DB >> 16293208

The roles of orphan nuclear receptors in the development and function of the immune system.

Ivan Dzhagalov1, Nu Zhang, You-Wen He.   

Abstract

Hormones and their receptors regulate cell growth, differentiation and apoptosis and also play important roles in immune function. Recent studies on the subfamily of the orphan nuclear receptors known as retinoid-acid related orphan receptors (ROR) have shed important insights on the roles of this group of nuclear proteins in the development and function of the immune system. RORalpha regulates inflammatory cytokine production in both innate and adaptive immune system while RORgamma regulates the normal development of T lymphocyte repertoire and secondary lymphoid organs.

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Year:  2004        PMID： 16293208

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


  9 in total

1.  Natural killer T-cell characterization through gene expression profiling: an account of versatility bridging T helper type 1 (Th1), Th2 and Th17 immune responses.

Authors:  Marcus Niemeyer; Alexandre Darmoise; Hans-Joachim Mollenkopf; Karin Hahnke; Robert Hurwitz; Gurdyal S Besra; Ulrich E Schaible; Stefan H E Kaufmann
Journal:  Immunology       Date:  2007-10-04       Impact factor: 7.397

2.  Live simian immunodeficiency virus vaccine correlate of protection: immune complex-inhibitory Fc receptor interactions that reduce target cell availability.

Authors:  Anthony J Smith; Stephen W Wietgrefe; Liang Shang; Cavan S Reilly; Peter J Southern; Katherine E Perkey; Lijie Duan; Heinz Kohler; Sybille Müller; James Robinson; John V Carlis; Qingsheng Li; R Paul Johnson; Ashley T Haase
Journal:  J Immunol       Date:  2014-08-20       Impact factor: 5.422

3.  RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with TH17 cells.

Authors:  Tae-Yoon Park; Sung-Dong Park; Jen-Young Cho; Jae-Seung Moon; Na-Yeon Kim; Kyungsoo Park; Rho Hyun Seong; Sang-Won Lee; Tomohiro Morio; Alfred L M Bothwell; Sang-Kyou Lee
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-19       Impact factor: 11.205

Review 4.  Neuroimmunomodulation in unipolar depression: a focus on chronobiology and chronotherapeutics.

Authors:  Harris Eyre; Bernhard T Baune
Journal:  J Neural Transm (Vienna)       Date:  2012-06-01       Impact factor: 3.575

5.  The orphan nuclear receptor RORalpha restrains adipocyte differentiation through a reduction of C/EBPbeta activity and perilipin gene expression.

Authors:  Nobumichi Ohoka; Shogo Kato; Yu Takahashi; Hidetoshi Hayashi; Ryuichiro Sato
Journal:  Mol Endocrinol       Date:  2009-03-26

Review 6.  Crosstalk between the circadian clock circuitry and the immune system.

Authors:  Nicolas Cermakian; Tanja Lange; Diego Golombek; Dipak Sarkar; Atsuhito Nakao; Shigenobu Shibata; Gianluigi Mazzoccoli
Journal:  Chronobiol Int       Date:  2013-05-22       Impact factor: 2.877

Review 7.  Multiple Roles of 25-Hydroxycholesterol in Lipid Metabolism, Antivirus Process, Inflammatory Response, and Cell Survival.

Authors:  Qin Cao; Zhongzhong Liu; Yan Xiong; Zibiao Zhong; Qifa Ye
Journal:  Oxid Med Cell Longev       Date:  2020-11-19       Impact factor: 6.543

8.  RORγt and RORα signature genes in human Th17 cells.

Authors:  Glenda Castro; Xuejun Liu; Karen Ngo; Aimee De Leon-Tabaldo; Shanrong Zhao; Rosa Luna-Roman; Jingxue Yu; Tinghua Cao; Robert Kuhn; Patrick Wilkinson; Krystal Herman; Marina I Nelen; Jonathan Blevitt; Xiaohua Xue; Anne Fourie; Wai-Ping Fung-Leung
Journal:  PLoS One       Date:  2017-08-01       Impact factor: 3.240

9.  Melatonin mediates monochromatic light-induced proliferation of T/B lymphocytes in the spleen via the membrane receptor or nuclear receptor.

Authors:  Juanjuan Xiong; Zixu Wang; Jing Cao; Yulan Dong; Yaoxing Chen
Journal:  Poult Sci       Date:  2020-06-24       Impact factor: 3.352
  9 in total

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