Literature DB >> 16293025

A pen injection device for self-administration of recombinant follicle-stimulating hormone for fertility treatments.

Samuel C Pang1.   

Abstract

A pen injection device modeled on the insulin pen used by diabetic patients has been introduced to deliver recombinant follicle-stimulating hormone to women undergoing controlled ovarian stimulation for in vitro fertilization or other forms of assisted reproductive technology. The pen device makes it easier and less painful for women to self-administer daily injections. The high precision and accuracy of the device enables physicians to fine-tune dosage. The woman simply inserts the multidose cartridge into the Puregon (Follistim) Pen, attaches a BD Micro-Fine Pen Needle, selects the prescribed dose on the dial at the base of the pen, inserts the needle subcutaneously and pushes the injection button to administer the injection. A fresh needle is used for each injection.

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Year:  2005        PMID: 16293025     DOI: 10.1586/17434440.2.1.27

Source DB:  PubMed          Journal:  Expert Rev Med Devices        ISSN: 1743-4440            Impact factor:   3.166


  6 in total

1.  Sequential (hFSH + recFSH) vs homogenous (hFSH or recFSH alone) stimulation: clinical and biochemical (cumulus cell gene expression) aspects.

Authors:  Timur Gurgan; Debbie Montjean; Aygul Demirol; Yves J R Menezo
Journal:  J Assist Reprod Genet       Date:  2014-03-18       Impact factor: 3.412

2.  Recombinant follitropin alfa/lutropin alfa in fertility treatment.

Authors:  Ahmed Gibreel; Siladitya Bhattacharya
Journal:  Biologics       Date:  2010-02-04

3.  Clinical outcomes following long GnRHa ovarian stimulation with highly purified human menopausal gonadotropin plus rFSH or rFSH in patients undergoing in vitro fertilization-embryo transfer: a multi-center randomized controlled trial.

Authors:  Li Shu; Qianhua Xu; Qingxia Meng; Xue Dai; Yun Zhang; Wei Zhou; Honggang Yi; Jinyong Liu; Chunxiang Wu; Zhen Hou; Yugui Cui; Tin Chiu Li; Jiayin Liu
Journal:  Ann Transl Med       Date:  2019-04

4.  A questionnaire-based survey to assess patient satisfaction, ease-of-learning, ease-of-use, injection site pain and overall patient satisfaction of the follitropin-alpha (Gonal-f) filled-by-mass (FbM) prefilled pen compared with other systems of gonadotrophin administration.

Authors:  Takafumi Utsunomiya; Atsushi Tanaka; Kenichi Tatsumi; Diego Ezcurra
Journal:  Reprod Biol Endocrinol       Date:  2012-11-20       Impact factor: 5.211

5.  Comparison of pregnancy outcome in half-dose Triptorelin and short-acting Decapeptyl in long protocol in ART cycles: A randomized clinical trial.

Authors:  Maryam Eftekhar; Elham Rahmani; Farnaz Mohammadian
Journal:  Iran J Reprod Med       Date:  2013-02

6.  Comparison of clinical efficacy between a single administration of long-acting gonadotrophin-releasing hormone agonist (GnRHa) and daily administrations of short-acting GnRHa in in vitro fertilization-embryo transfer cycles.

Authors:  Kang Woo Cheon; Sang Jin Song; Bum Chae Choi; Seung Chul Lee; Hong Bok Lee; Seung Youn Yu; Keun Jai Yoo
Journal:  J Korean Med Sci       Date:  2008-08       Impact factor: 2.153

  6 in total

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