Literature DB >> 16292884

Role of nanobiotechnology in developing personalized medicine for cancer.

K K Jain1.   

Abstract

Personalized medicine simply means the prescription of specific therapeutics best suited for an individual. Personalization of cancer therapies is based on a better understanding of the disease at the molecular level. Nanotechnology will play an important role in this area. Nanobiotechnology is being used to refine discovery of biomarkers, molecular diagnostics, drug discovery and drug delivery, which are important basic components of personalized medicine and are applicable to management of cancer as well. Examples are given of the application of quantum dots, gold nanoparticles, and molecular imaging in diagnostics and combination with therapeutics -- another important feature of personalized medicine. Personalized medicine is beginning to be recognized and is expected to become a part of medical practice within the next decade. Personalized management of cancer, facilitated by nanobiotechnology, is expected to enable early detection of cancer, more effective and less toxic treatment increasing the chances of cure.

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Year:  2005        PMID: 16292884     DOI: 10.1177/153303460500400608

Source DB:  PubMed          Journal:  Technol Cancer Res Treat        ISSN: 1533-0338


  18 in total

1.  Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery.

Authors:  Huanyu Dou; Christopher J Destache; Justin R Morehead; R Lee Mosley; Michael D Boska; Jeffrey Kingsley; Santhi Gorantla; Larisa Poluektova; Jay A Nelson; Mahesh Chaubal; Jane Werling; James Kipp; Barrett E Rabinow; Howard E Gendelman
Journal:  Blood       Date:  2006-06-29       Impact factor: 22.113

Review 2.  Nanoparticles: pharmacological and toxicological significance.

Authors:  C Medina; M J Santos-Martinez; A Radomski; O I Corrigan; M W Radomski
Journal:  Br J Pharmacol       Date:  2007-01-22       Impact factor: 8.739

Review 3.  Utilization of monoclonal antibody-targeted nanomaterials in the treatment of cancer.

Authors:  Daniel C Julien; Steven Behnke; Guankui Wang; Gordon K Murdoch; Rodney A Hill
Journal:  MAbs       Date:  2011-09-01       Impact factor: 5.857

Review 4.  Review on early technology assessments of nanotechnologies in oncology.

Authors:  Valesca P Retèl; Marjan J M Hummel; Wim H van Harten
Journal:  Mol Oncol       Date:  2009-05-20       Impact factor: 6.603

5.  From bench to bedside: the growing use of translational research in cancer medicine.

Authors:  Erin M Goldblatt; Wen-Hwa Lee
Journal:  Am J Transl Res       Date:  2010-01-01       Impact factor: 4.060

6.  Toxic effects of gold nanoparticles on Salmonella typhimurium bacteria.

Authors:  Shuguang Wang; Rasheeda Lawson; Paresh C Ray; Hongtao Yu
Journal:  Toxicol Ind Health       Date:  2011-03-17       Impact factor: 2.273

Review 7.  A tumor multicomponent targeting chemoimmune drug delivery system for reprograming the tumor microenvironment and personalized cancer therapy.

Authors:  Samaresh Sau; Katyayani Tatiparti; Hashem O Alsaab; Sushil K Kashaw; Arun K Iyer
Journal:  Drug Discov Today       Date:  2018-03-15       Impact factor: 7.851

8.  Tracking the relative in vivo pharmacokinetics of nanoparticles with PARACEST MRI.

Authors:  M Meser Ali; Byunghee Yoo; Mark D Pagel
Journal:  Mol Pharm       Date:  2009 Sep-Oct       Impact factor: 4.939

Review 9.  Nanoparticle-based targeted drug delivery.

Authors:  Rajesh Singh; James W Lillard
Journal:  Exp Mol Pathol       Date:  2009-01-07       Impact factor: 3.362

10.  Visualizing human prostate cancer cells in mouse skeleton using bioconjugated near-infrared fluorescent quantum dots.

Authors:  Chunmeng Shi; Ying Zhu; Zhihui Xie; Weiping Qian; Chia-Ling Hsieh; Shuming Nie; Yongping Su; Haiyen E Zhau; Leland W K Chung
Journal:  Urology       Date:  2009-05-09       Impact factor: 2.649

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