Literature DB >> 16292586

Sudden cardiac death during anabolic steroid abuse: morphologic and toxicologic findings in two fatal cases of bodybuilders.

Vittorio Fineschi1, Irene Riezzo, Fabio Centini, Enrico Silingardi, Manuela Licata, Giovanni Beduschi, Steven B Karch.   

Abstract

We report two cases of sudden cardiac death (SCD) involving previously healthy bodybuilders who were chronic androgenic-anabolic steroids users. In both instances, autopsies, histology of the organs, and toxicologic screening were performed. Our findings support an emerging consensus that the effects of vigorous weight training, combined with anabolic steroid use and increased androgen sensitivity, may predispose these young men to myocardial injury and even SCD.

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Year:  2005        PMID: 16292586     DOI: 10.1007/s00414-005-0055-9

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


  19 in total

1.  Myocardial contraction bands. Definition, quantification and significance in forensic pathology.

Authors:  G Baroldi; R E Mittleman; M Parolini; M D Silver; V Fineschi
Journal:  Int J Legal Med       Date:  2001-12       Impact factor: 2.686

2.  Liver pathology associated with the use of anabolic-androgenic steroids.

Authors:  K L Søe; M Søe; C Gluud
Journal:  Liver       Date:  1992-04

3.  [Myocardial infarction and death of a body builder after using anabolic steroids].

Authors:  K K Lyngberg
Journal:  Ugeskr Laeger       Date:  1991-02-18

4.  Anabolic steroid abuse and cardiac sudden death: a pathologic study.

Authors:  V Fineschi; G Baroldi; F Monciotti; L Paglicci Reattelli; E Turillazzi
Journal:  Arch Pathol Lab Med       Date:  2001-02       Impact factor: 5.534

Review 5.  The cardiac toxicity of anabolic steroids.

Authors:  M L Sullivan; C M Martinez; P Gennis; E J Gallagher
Journal:  Prog Cardiovasc Dis       Date:  1998 Jul-Aug       Impact factor: 8.194

6.  Are the cardiac effects of anabolic steroid abuse in strength athletes reversible?

Authors:  A Urhausen; T Albers; W Kindermann
Journal:  Heart       Date:  2004-05       Impact factor: 5.994

7.  Sudden cardiac death in a child affected by Prader-Willi syndrome.

Authors:  Cristoforo Pomara; Stefano D'Errico; Irene Riezzo; Gian Pio de Cillis; Vittorio Fineschi
Journal:  Int J Legal Med       Date:  2005-03-05       Impact factor: 2.686

8.  Toxic effects of anabolic-androgenic steroids in primary rat hepatic cell cultures.

Authors:  A A Welder; J W Robertson; R B Melchert
Journal:  J Pharmacol Toxicol Methods       Date:  1995-08       Impact factor: 1.950

9.  Sudden cardiac death in a 20-year-old bodybuilder using anabolic steroids.

Authors:  R D Dickerman; F Schaller; I Prather; W J McConathy
Journal:  Cardiology       Date:  1995       Impact factor: 1.869

Review 10.  Cardiovascular effects of androgenic-anabolic steroids.

Authors:  R B Melchert; A A Welder
Journal:  Med Sci Sports Exerc       Date:  1995-09       Impact factor: 5.411

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  27 in total

1.  Sudden death due to pulmonary embolism from right atrial myxoma.

Authors:  T Fracasso; K Varchmin-Schultheiss
Journal:  Int J Legal Med       Date:  2009-01-06       Impact factor: 2.686

Review 2.  Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: a looming public health concern?

Authors:  Gen Kanayama; James I Hudson; Harrison G Pope
Journal:  Drug Alcohol Depend       Date:  2008-07-02       Impact factor: 4.492

3.  Detection and quantification of 12 anabolic steroids and analogs in human whole blood and 20 in hair using LC-HRMS/MS: application to real cases.

Authors:  Nicolas Fabresse; Stanislas Grassin-Delyle; Isabelle Etting; Jean-Claude Alvarez
Journal:  Int J Legal Med       Date:  2017-02-24       Impact factor: 2.686

Review 4.  Medico-legal perspectives on sudden cardiac death in young athletes.

Authors:  Antonio Oliva; Vincenzo M Grassi; Oscar Campuzano; Maria Brion; Vincenzo Arena; Sara Partemi; Monica Coll; Vincenzo L Pascali; Josep Brugada; Angel Carracedo; Ramon Brugada
Journal:  Int J Legal Med       Date:  2016-09-21       Impact factor: 2.686

5.  Pathology of fatal traumatic and nontraumatic clostridial gas gangrene: a histopathological, immunohistochemical, and ultrastructural study of six autopsy cases.

Authors:  Michael Tsokos; Sarah Schalinski; Friedrich Paulsen; Jan P Sperhake; Klaus Püschel; Ingo Sobottka
Journal:  Int J Legal Med       Date:  2007-03-17       Impact factor: 2.686

Review 6.  Cardiac and metabolic effects of anabolic-androgenic steroid abuse on lipids, blood pressure, left ventricular dimensions, and rhythm.

Authors:  Suraj Achar; Armand Rostamian; Sanjiv M Narayan
Journal:  Am J Cardiol       Date:  2010-09-15       Impact factor: 2.778

7.  Long-term anabolic-androgenic steroid use is associated with left ventricular dysfunction.

Authors:  Aaron L Baggish; Rory B Weiner; Gen Kanayama; James I Hudson; Michael H Picard; Adolph M Hutter; Harrison G Pope
Journal:  Circ Heart Fail       Date:  2010-04-27       Impact factor: 8.790

8.  Suicidal poisoning with mercaptodimethur-morphological findings and toxicological analysis.

Authors:  A Thierauf; H Gnann; M Bohnert; B Vennemann; V Auwärter; W Weinmann
Journal:  Int J Legal Med       Date:  2009-01-16       Impact factor: 2.686

9.  Ventricular structure, function, and focal fibrosis in anabolic steroid users: a CMR study.

Authors:  Peter J Angell; Tevfik F Ismail; Andrew Jabbour; Gillian Smith; Annette Dahl; Ricardo Wage; Greg Whyte; Daniel J Green; Sanjay Prasad; Keith George
Journal:  Eur J Appl Physiol       Date:  2014-01-28       Impact factor: 3.078

10.  Stevens-Johnson syndrome and abuse of anabolic steroids.

Authors:  Serena Cocca; Massimo Viviano
Journal:  J Korean Assoc Oral Maxillofac Surg       Date:  2017-02-20
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