Literature DB >> 16292390

Solid phase synthesis of a spiro[5.5]ketal library.

Stefan Sommer1, Herbert Waldmann.   

Abstract

A spiro[5.5]ketal library embodying the core structure of numerous biologically active natural products was synthesized employing a double intramolecular hetero Michael reaction as a key transformation.

Mesh:

Year:  2005        PMID: 16292390     DOI: 10.1039/b511177c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Racemic hemiacetals as oxygen-centered pronucleophiles triggering cascade 1,4-addition/Michael reaction through dynamic kinetic resolution under iminium catalysis. Development and mechanistic insights.

Authors:  Ane Orue; Uxue Uria; David Roca-López; Ignacio Delso; Efraím Reyes; Luisa Carrillo; Pedro Merino; Jose L Vicario
Journal:  Chem Sci       Date:  2017-01-30       Impact factor: 9.825

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.