PURPOSE: To compare the HRCT score by Oikonomou and air trapping in expiratory scans with pulmonary functional tests and evaluate which radiological criteria are more useful to predict clinical impairment. MATERIALS AND METHODS: From January to September 2003, pulmonary HRCT study was performed in 37 patients (23 males), aged between 7 and 41 years, with cystic fibrosis. In the same day of CT examination they also received a complete functional evaluation. HRCT studies were evaluated by three radiologists blinded to the clinical data and were correlated with the lung function tests. RESULTS: We obtained a high correlation (p=0.01) for two of the HRCT signs: extent of mucus plugging and mosaic perfusion pattern and all function tests. DISCUSSION: Previous studies have demonstrated good correlation between lung function tests, in particular with FEV1,and HRCT signs. Our study differed from previous ones in that we analysed the correlation between lung function tests and with both single and combined CT criteria. CONCLUSIONS: Our results suggest that a simplified HRCT score could be useful to evaluate patients with cystic fibrosis.
PURPOSE: To compare the HRCT score by Oikonomou and air trapping in expiratory scans with pulmonary functional tests and evaluate which radiological criteria are more useful to predict clinical impairment. MATERIALS AND METHODS: From January to September 2003, pulmonary HRCT study was performed in 37 patients (23 males), aged between 7 and 41 years, with cystic fibrosis. In the same day of CT examination they also received a complete functional evaluation. HRCT studies were evaluated by three radiologists blinded to the clinical data and were correlated with the lung function tests. RESULTS: We obtained a high correlation (p=0.01) for two of the HRCT signs: extent of mucus plugging and mosaic perfusion pattern and all function tests. DISCUSSION: Previous studies have demonstrated good correlation between lung function tests, in particular with FEV1,and HRCT signs. Our study differed from previous ones in that we analysed the correlation between lung function tests and with both single and combined CT criteria. CONCLUSIONS: Our results suggest that a simplified HRCT score could be useful to evaluate patients with cystic fibrosis.
Authors: Corrado Tagliati; Cecilia Lanza; Giovanni Pieroni; Lucia Amici; Marina Carotti; Gian Marco Giuseppetti; Andrea Giovagnoni Journal: Radiol Med Date: 2020-11-16 Impact factor: 3.469