| Literature DB >> 16291259 |
Srigiridhar Kotamraju1, Shasi Kalivendi, Tiesong Shang, B Kalyanaraman.
Abstract
In this chapter, oxidant-induced transferrin receptor-mediated iron-signaling and apoptosis are described in endothelial and neuronal cells exposed to oxidants. The role of nitric oxide in the regulation of iron homeostasis and oxidant-induced apoptosis is described. The interrelationship between oxidative stress, iron-signaling, and nitric oxide-dependent proteasomal function provides a rational mechanism that connects both oxidative and nitrative modifications.Entities:
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Year: 2005 PMID： 16291259 DOI： 10.1016/S0076-6879(05)96044-8
Source DB: PubMed Journal: Methods Enzymol ISSN： 0076-6879 Impact factor: 1.600