Literature DB >> 16290320

Melanocortin-4 receptors, beta-MSH and leptin: key elements in the satiety pathway.

Joanne A Harrold1, Gareth Williams.   

Abstract

This paper reviews aspects of our research, focusing on the role of the melanocortin system in the central regulation of feeding and energy balance, which was begun in 1997. It describes data from successive physiological studies, concerning the identity of the appetite-regulating melanocortin receptor, melanocortin-4 receptor (MC4R) regulation with altered nutritional status, the role of MC4R in dietary obesity and the identity of the endogenous MC4R ligand.

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Year:  2005        PMID： 16290320     DOI： 10.1016/j.peptides.2005.01.030

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  14 in total

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Review 2.  GENETIC AND EPIGENETIC CAUSES OF OBESITY.

Authors:  Vidhu V Thaker
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3.  Control of food intake by MC4-R signaling in the lateral hypothalamus, nucleus accumbens shell and ventral tegmental area: interactions with ethanol.

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Journal:  Reprod Toxicol       Date:  2016-10-17       Impact factor: 3.143

5.  Unique leptin trafficking by a tailless receptor.

Authors:  Hong Tu; Hung Hsuchou; Abba J Kastin; Xiaojun Wu; Weihong Pan
Journal:  FASEB J       Date:  2010-03-11       Impact factor: 5.191

6.  The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.

Authors:  Ya-Xiong Tao
Journal:  Endocr Rev       Date:  2010-02-26       Impact factor: 19.871

7.  Diet-induced obesity and prenatal undernutrition lead to differential neuroendocrine gene expression in the hypothalamic arcuate nuclei.

Authors:  Mhoyra Fraser; Charisma K Dhaliwal; Mark H Vickers; Stefan O Krechowec; Bernhard H Breier
Journal:  Endocrine       Date:  2016-03-16       Impact factor: 3.633

8.  Agouti-related peptide and MC3/4 receptor agonists both inhibit excitatory hypothalamic ventromedial nucleus neurons.

Authors:  Li-Ying Fu; Anthony N van den Pol
Journal:  J Neurosci       Date:  2008-05-21       Impact factor: 6.167

Review 9.  Pharmacogenetic Associations of Antipsychotic Drug-Related Weight Gain: A Systematic Review and Meta-analysis.

Authors:  Jian-Ping Zhang; Todd Lencz; Ryan X Zhang; Masahiro Nitta; Lawrence Maayan; Majnu John; Delbert G Robinson; W Wolfgang Fleischhacker; Rene S Kahn; Roel A Ophoff; John M Kane; Anil K Malhotra; Christoph U Correll
Journal:  Schizophr Bull       Date:  2016-05-23       Impact factor: 9.306

10.  The central melanocortin system directly controls peripheral lipid metabolism.

Authors:  Ruben Nogueiras; Petra Wiedmer; Diego Perez-Tilve; Christelle Veyrat-Durebex; Julia M Keogh; Gregory M Sutton; Paul T Pfluger; Tamara R Castaneda; Susanne Neschen; Susanna M Hofmann; Philip N Howles; Donald A Morgan; Stephen C Benoit; Ildiko Szanto; Brigitte Schrott; Annette Schürmann; Hans-Georg Joost; Craig Hammond; David Y Hui; Stephen C Woods; Kamal Rahmouni; Andrew A Butler; I Sadaf Farooqi; Stephen O'Rahilly; Françoise Rohner-Jeanrenaud; Matthias H Tschöp
Journal:  J Clin Invest       Date:  2007-11       Impact factor: 14.808
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