Literature DB >> 16289814

Indoloprodigiosins from the C-10 bipyrrolic precursor: new antiproliferative prodigiosin analogs.

Carmen M Baldino1, Jonathan Parr, Christopher J Wilson, Shi-Chung Ng, Daniel Yohannes, Harry H Wasserman.   

Abstract

The condensation of the C-10 methoxybipyrrole precursor (3) of prodigiosin with indoles and a related pyrrole derivative yields novel analogs of prodigiosin. Biological evaluation of these products revealed compounds that inhibit cancer cell proliferation from 50 nM to 50 microM.

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Year:  2005        PMID： 16289814     DOI： 10.1016/j.bmcl.2005.10.027

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  5 in total

1.  Antimicrobial activity of prodigiosin isolated from Serratia marcescens UFPEDA 398.

Authors:  J C Lapenda; P A Silva; M C Vicalvi; K X F R Sena; S C Nascimento
Journal:  World J Microbiol Biotechnol       Date:  2014-12-31       Impact factor: 3.312

2.  Synthesis, Anticancer Potential and Comprehensive Toxicity Studies of Novel Brominated Derivatives of Bacterial Biopigment Prodigiosin from Serratia marcescens ATCC 27117.

Authors:  Jelena Lazic; Sanja Skaro Bogojevic; Sandra Vojnovic; Ivana Aleksic; Dusan Milivojevic; Martin Kretzschmar; Tanja Gulder; Milos Petkovic; Jasmina Nikodinovic-Runic
Journal:  Molecules       Date:  2022-06-09       Impact factor: 4.927

Review 3.  Prodigiosin and its potential applications.

Authors:  N Darshan; H K Manonmani
Journal:  J Food Sci Technol       Date:  2015-01-24       Impact factor: 2.701

4.  Undecylprodigiosin induced apoptosis in P388 cancer cells is associated with its binding to ribosome.

Authors:  Ping Liu; Yuan-yuan Wang; Xin Qi; QianQun Gu; Meiyu Geng; Jing Li
Journal:  PLoS One       Date:  2013-06-14       Impact factor: 3.240

5.  Study on the Anticancer Activity of Prodigiosin from Variants of Serratia Marcescens QBN VTCC 910026.

Authors:  Sy Le Thanh Nguyen; Tien Cuong Nguyen; Thi Tuyen Do; Trong Luong Vu; Thi Thao Nguyen; Thi Thao Do; Thi Hien Trang Nguyen; Thanh Hoang Le; Dinh Kha Trinh; Thi Anh Tuyet Nguyen
Journal:  Biomed Res Int       Date:  2022-04-25       Impact factor: 3.246
  5 in total

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