| Literature DB >> 16289166 |
Paul N Newton1, Steven Ward, Brian J Angus, Wirongrong Chierakul, Arjen Dondorp, Ronnatrai Ruangveerayuth, Kamolrat Silamut, Pramote Teerapong, Yupin Suputtamongkol, Sornchai Looareesuwan, Nicholas J White.
Abstract
A patient admitted with severe Plasmodium falciparum malaria in western Thailand had an early treatment failure with quinine, despite full dosing. Plasma quinine concentrations were subtherapeutic. Abnormal quinine pharmacokinetics may explain sporadic reports of quinine treatment failures in severe malaria.Entities:
Mesh：
Substances：
Year: 2005 PMID： 16289166 DOI： 10.1016/j.trstmh.2005.01.008
Source DB: PubMed Journal: Trans R Soc Trop Med Hyg ISSN： 0035-9203 Impact factor: 2.184