| Literature DB >> 16288524 |
Paul A Alexander1, Stephen P Marsden, Dulce M Muñoz Subtil, John C Reader.
Abstract
[reaction: see text] A practical and general two-step synthesis of carbamate-protected (E)-vinylglycines from aliphatic aldehydes is reported. The key step involves the kinetic alpha-protonation of dianionic dienolates derived from dehydroamino acids.Entities:
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Year: 2005 PMID: 16288524 DOI: 10.1021/ol052139q
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005