Literature DB >> 16287990

The KCNQ1 potassium channel: from gene to physiological function.

Thomas Jespersen1, Morten Grunnet, Søren-Peter Olesen.   

Abstract

The voltage-gated KCNQ1 (KvLQT1, Kv7.1) potassium channel plays a crucial role in shaping the cardiac action potential as well as in controlling the water and salt homeostasis in several epithelial tissues. KCNQ1 channels in these tissues are tightly regulated by auxiliary proteins and accessory factors, capable of modulating the properties of the channel complexes. This paper reviews the current knowledge about the KCNQ1 channel with a major focus on interacting proteins and physiological functions.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 16287990     DOI： 10.1152/physiol.00031.2005

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  107 in total

1.  KCNE3 acts by promoting voltage sensor activation in KCNQ1.

Authors:  Rene Barro-Soria; Marta E Perez; H Peter Larsson
Journal:  Proc Natl Acad Sci U S A       Date:  2015-12-14       Impact factor: 11.205

2.  Up-regulation of Kv7.1 channels in thromboxane A2-induced colonic cancer cell proliferation.

Authors:  Takahiro Shimizu; Takuto Fujii; Yuji Takahashi; Yuta Takahashi; Tomoyuki Suzuki; Masashi Ukai; Katsunori Tauchi; Naoki Horikawa; Kazuhiro Tsukada; Hideki Sakai
Journal:  Pflugers Arch       Date:  2013-09-01       Impact factor: 3.657

3.  Inactivation as a new regulatory mechanism for neuronal Kv7 channels.

Authors:  Henrik Sindal Jensen; Morten Grunnet; Søren-Peter Olesen
Journal:  Biophys J       Date:  2007-01-19       Impact factor: 4.033

4.  Structural models for the KCNQ1 voltage-gated potassium channel.

Authors:  Jarrod A Smith; Carlos G Vanoye; Alfred L George; Jens Meiler; Charles R Sanders
Journal:  Biochemistry       Date:  2007-11-14       Impact factor: 3.162

5.  Probing the Dynamics and Structural Topology of the Reconstituted Human KCNQ1 Voltage Sensor Domain (Q1-VSD) in Lipid Bilayers Using Electron Paramagnetic Resonance Spectroscopy.

Authors:  Gunjan Dixit; Indra D Sahu; Warren D Reynolds; Tessa M Wadsworth; Benjamin D Harding; Colleen K Jaycox; Carole Dabney-Smith; Charles R Sanders; Gary A Lorigan
Journal:  Biochemistry       Date:  2019-01-30       Impact factor: 3.162

6.  NMR resonance assignments and secondary structure of a mutant form of the human KCNE1 channel accessory protein that exhibits KCNE3-like function.

Authors:  Cheryl L Law; Charles R Sanders
Journal:  Biomol NMR Assign       Date:  2019-01-02       Impact factor: 0.746

7.  Mechano- and chemosensitivity of rat nodose neurones--selective excitatory effects of prostacyclin.

Authors:  Vladislav Snitsarev; Carol A Whiteis; Mark W Chapleau; François M Abboud
Journal:  J Physiol       Date:  2007-05-03       Impact factor: 5.182

8.  Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines.

Authors:  José M Fernández-Fernández; Yaniré N Andrade; Maite Arniges; Jacqueline Fernandes; Cristina Plata; Francisca Rubio-Moscardo; Esther Vázquez; Miguel A Valverde
Journal:  Pflugers Arch       Date:  2008-05-06       Impact factor: 3.657

9.  Estrogen-related receptor γ (ERRγ) regulates oxygen-dependent expression of voltage-gated potassium (K+) channels and tissue kallikrein during human trophoblast differentiation.

Authors:  Yanmin Luo; Premlata Kumar; Carole R Mendelson
Journal:  Mol Endocrinol       Date:  2013-04-12

10.  Regulation of membrane KCNQ1/KCNE1 channel density by sphingomyelin synthase 1.

Authors:  Meikui Wu; Makoto Takemoto; Makoto Taniguchi; Toru Takumi; Toshiro Okazaki; Wen-Jie Song
Journal:  Am J Physiol Cell Physiol       Date:  2016-05-18       Impact factor: 4.249
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.