Literature DB >> 16287266

Ruthenium-catalyzed cycloaddition of alkynes and organic azides.

Li Zhang1, Xinguo Chen, Peng Xue, Herman H Y Sun, Ian D Williams, K Barry Sharpless, Valery V Fokin, Guochen Jia.   

Abstract

Cp*RuCl(PPh3)2 is an effective catalyst for the regioselective "fusion" of organic azides and terminal alkynes, producing 1,5-disubstituted 1,2,3-triazoles. Internal alkynes also participate in this catalysis, resulting in fully substituted 1,2,3-triazoles.

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Year:  2005        PMID： 16287266     DOI： 10.1021/ja054114s

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  94 in total

1.  α-Azido ketones. Part 7: synthesis of 1,4-disubstituted triazoles by the "click" reaction of various terminal acetylenes with phenacyl azides or α-azidobenzo(hetera)cyclanones.

Authors:  Krisztina Kónya; Szabolcs Fekete; Anita Abrahám; Tamás Patonay
Journal:  Mol Divers       Date:  2012-02-04       Impact factor: 2.943

2.  Development of stable phosphohistidine analogues.

Authors:  Jung-Min Kee; Bryeanna Villani; Laura R Carpenter; Tom W Muir
Journal:  J Am Chem Soc       Date:  2010-10-20       Impact factor: 15.419

3.  Direct Pd-catalyzed arylation of 1,2,3-triazoles.

Authors:  Stepan Chuprakov; Natalia Chernyak; Alexander S Dudnik; Vladimir Gevorgyan
Journal:  Org Lett       Date:  2007-05-10       Impact factor: 6.005

4.  A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling.

Authors:  Henning S G Beckmann; Feilin Nie; Caroline E Hagerman; Henrik Johansson; Yaw Sing Tan; David Wilcke; David R Spring
Journal:  Nat Chem       Date:  2013-08-25       Impact factor: 24.427

Review 5.  Computational studies on the regioselectivity of metal-catalyzed synthesis of 1,2,3 triazoles via click reaction: a review.

Authors:  Tayebeh Hosseinnejad; Bahareh Fattahi; Majid M Heravi
Journal:  J Mol Model       Date:  2015-09-18       Impact factor: 1.810

6.  Antitubercular activity of 1,2,3-triazolyl fatty acid derivatives.

Authors:  Diego G Ghiano; Agustina de la Iglesia; Nina Liu; Peter J Tonge; Héctor R Morbidoni; Guillermo R Labadie
Journal:  Eur J Med Chem       Date:  2016-09-28       Impact factor: 6.514

7.  Regioselective intramolecular dipolar cycloaddition of azides and unsymmetrical alkynes.

Authors:  Ryan A Brawn; Morgan Welzel; Jason T Lowe; James S Panek
Journal:  Org Lett       Date:  2010-01-15       Impact factor: 6.005

8.  Copper(I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes.

Authors:  Jason E Hein; Jonathan C Tripp; Larissa B Krasnova; K Barry Sharpless; Valery V Fokin
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

9.  Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site.

Authors:  Rajesh Karuturi; Rami A Al-Horani; Shrenik C Mehta; David Gailani; Umesh R Desai
Journal:  J Med Chem       Date:  2013-03-18       Impact factor: 7.446

10.  Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles.

Authors:  Tony Horneff; Stepan Chuprakov; Natalia Chernyak; Vladimir Gevorgyan; Valery V Fokin
Journal:  J Am Chem Soc       Date:  2008-10-15       Impact factor: 15.419
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