Literature DB >> 16287246

Surface modification to reduce nonspecific binding of quantum dots in live cell assays.

Elizabeth L Bentzen1, Ian D Tomlinson, John Mason, Paul Gresch, Michael R Warnement, David Wright, Elaine Sanders-Bush, Randy Blakely, Sandra J Rosenthal.   

Abstract

Nonspecific binding is a frequently encountered problem with fluorescent labeling of tissue cultures when labeled with quantum dots. In these studies various cell lines were examined for nonspecific binding. Evidence suggests that nonspecific binding is related to cell type and may be significantly reduced by functionalizing quantum dots with poly(ethylene glycol) ligands (PEG). The length of PEG required to give a significant reduction in nonspecific binding may be as short as 12-14 ethylene glycol units.

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Year:  2005        PMID： 16287246     DOI： 10.1021/bc0502006

Source DB:  PubMed          Journal:  Bioconjug Chem        ISSN： 1043-1802            Impact factor:   4.774


  53 in total

Review 1.  Biocompatible quantum dots for biological applications.

Authors:  Sandra J Rosenthal; Jerry C Chang; Oleg Kovtun; James R McBride; Ian D Tomlinson
Journal:  Chem Biol       Date:  2011-01-28

Review 2.  Probing cellular events, one quantum dot at a time.

Authors:  Fabien Pinaud; Samuel Clarke; Assa Sittner; Maxime Dahan
Journal:  Nat Methods       Date:  2010-03-30       Impact factor: 28.547

3.  Self-assembled quantum dot-peptide bioconjugates for selective intracellular delivery.

Authors:  James B Delehanty; Igor L Medintz; Thomas Pons; Florence M Brunel; Philip E Dawson; Hedi Mattoussi
Journal:  Bioconjug Chem       Date:  2006 Jul-Aug       Impact factor: 4.774

4.  Intracellular delivery of VIP-grafted sterically stabilized phospholipid mixed nanomicelles in human breast cancer cells.

Authors:  Israel Rubinstein; Imre Soos; Hayat Onyuksel
Journal:  Chem Biol Interact       Date:  2007-04-06       Impact factor: 5.192

5.  Synthesis, Surface Studies, Composition and Structural Characterization of CdSe, Core/Shell, and Biologically Active Nanocrystals.

Authors:  Sandra J Rosenthal; James McBride; Stephen J Pennycook; Leonard C Feldman
Journal:  Surf Sci Rep       Date:  2007-04-30       Impact factor: 12.267

6.  Compact biocompatible quantum dots via RAFT-mediated synthesis of imidazole-based random copolymer ligand.

Authors:  Wenhao Liu; Andrew B Greytak; Jungmin Lee; Cliff R Wong; Jongnam Park; Lisa F Marshall; Wen Jiang; Peter N Curtin; Alice Y Ting; Daniel G Nocera; Dai Fukumura; Rakesh K Jain; Moungi G Bawendi
Journal:  J Am Chem Soc       Date:  2010-01-20       Impact factor: 15.419

7.  Surface engineering of quantum dots for in vivo vascular imaging.

Authors:  Ashwath Jayagopal; Patricia K Russ; Frederick R Haselton
Journal:  Bioconjug Chem       Date:  2007-08-31       Impact factor: 4.774

8.  Single Quantum Dot Tracking Illuminates Neuroscience at the Nanoscale.

Authors:  Oleg Kovtun; Ian D Tomlinson; Danielle M Bailey; Lucas B Thal; Emily J Ross; Lauren Harris; Michael P Frankland; Riley S Ferguson; Zachary Glaser; Jonathan Greer; Sandra J Rosenthal
Journal:  Chem Phys Lett       Date:  2018-06-19       Impact factor: 2.328

9.  Compact cysteine-coated CdSe(ZnCdS) quantum dots for in vivo applications.

Authors:  Wenhao Liu; Hak Soo Choi; John P Zimmer; Eiichi Tanaka; John V Frangioni; Moungi Bawendi
Journal:  J Am Chem Soc       Date:  2007-11-06       Impact factor: 15.419

Review 10.  Semiconductor quantum dots for bioimaging and biodiagnostic applications.

Authors:  Brad A Kairdolf; Andrew M Smith; Todd H Stokes; May D Wang; Andrew N Young; Shuming Nie
Journal:  Annu Rev Anal Chem (Palo Alto Calif)       Date:  2013-03-20       Impact factor: 10.745
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