| Literature DB >> 16287045 |
John Hardy1, Sonja Scholz, Whitney Evans, Lev Goldfarb, Andrew Singleton.
Abstract
Using the well-characterized, human diversity sample series, we show that the V129 prion allele has a very high frequency in South American populations relative to the East Asian populations from which it arose. We suggest there has been selection at the prion locus, possibly mediated by Kuru-like diseases, which has influenced its allele frequency. (c) 2005 Wiley-Liss, Inc.Entities:
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Year: 2006 PMID： 16287045 DOI： 10.1002/ajmg.b.30248
Source DB: PubMed Journal: Am J Med Genet B Neuropsychiatr Genet ISSN： 1552-4841 Impact factor: 3.568