Literature DB >> 16286315

Comparative studies on the camptothecin content from Nothapodytes foetida and Ophiorrhiza species.

G Roja1.   

Abstract

Camptothecin is an anticancer quinoline alkaloid effective against colon cancer. It acts by inhibition of the enzyme DNA topoisomerase I. A comparative study of camptothecin from the indigenous plants namely Nothapodytes foetida, Ophiorrhiza mungos and Ophiorrhiza rugosa indicated highest yields of camptothecin and 9-methoxy camptothecin in N. foetida. The other two plants O. mungos and O. rugosa contained low levels of alkaloids.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16286315     DOI： 10.1080/15216540500092898

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  3 in total

1.  Evaluating Nothapodytes nimmoniana population from three localities of Western Ghats using camptothecin as phytochemical marker and selection of elites using a new-content range chart method.

Authors:  Gireesh Ankad; Vinayak Upadhya; Sandeep R Pai; Mansingraj S Nimbalkar; Harsha V Hegde; Rajesh K Joshi; Sanjiva D Kholkute
Journal:  Pharmacogn Mag       Date:  2015 Jan-Mar       Impact factor: 1.085

2.  Enhanced production of camptothecin by immobilized callus of Ophiorrhiza mungos and a bioinformatic insight into its potential antiviral effect against SARS-CoV-2.

Authors:  Rajesh Mamkulathil Devasia; Mohammad Altaf; Abdulwahed Fahad Alrefaei; Salim Manoharadas
Journal:  J King Saud Univ Sci       Date:  2021-01-21

3.  Compound Specific Extraction of Camptothecin from Nothapodytes nimmoniana and Piperine from Piper nigrum Using Accelerated Solvent Extractor.

Authors:  Vinayak Upadhya; Sandeep R Pai; Ajay K Sharma; Harsha V Hegde; Sanjiva D Kholkute; Rajesh K Joshi
Journal:  J Anal Methods Chem       Date:  2014-01-02       Impact factor: 2.193
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.