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Literature DB >> 1628537

Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention.

N P Vermeulen¹, J G Bessems, R Van de Straat.

Abstract

Entities: Chemical Disease

Mesh：

Substances：
Acetaminophen

Year: 1992 PMID： 1628537 DOI： 10.3109/03602539208996298

Source DB: PubMed Journal: Drug Metab Rev ISSN： 0360-2532 Impact factor: 4.518

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37 in total

1. Differential effects of acetaminophen on enzymatic and non-enzymatic antioxidant factors and plasma total antioxidant capacity in developing and adult rats.

Authors: Abolfazl Dadkhah; Faezeh Fatemi; Somaieh Kazemnejad; Yusef Rasmi; Javad Ashrafi-Helan; Abdolamir Allameh
Journal: Mol Cell Biochem Date: 2006-01 Impact factor: 3.396

2. Defensive nature of Sargassum polycystum (Brown alga) against acetaminophen-induced toxic hepatitis in rats: role of drug metabolizing microsomal enzyme system, tumor necrosis factor-alpha and fate of liver cell structural integrity.

Authors: H Balaji Raghavendran; A Sathivel; T Devaki
Journal: World J Gastroenterol Date: 2006-06-28 Impact factor: 5.742

3. Protective effect of Premna tomentosa extract (L. verbanacae) on acetaminophen-induced mitochondrial dysfunction in rats.

Authors: K Pandima Devi; M Sreepriya; K Balakrishna; T Devaki
Journal: Mol Cell Biochem Date: 2005-04 Impact factor: 3.396

4. Mice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicity.

Authors: Xin Gen Lei; Jian-Hong Zhu; James P McClung; Manuel Aregullin; Carol A Roneker
Journal: Biochem J Date: 2006-11-01 Impact factor: 3.857

5. Potential physiological effects of pharmaceutical compounds in Atlantic salmon (Salmo salar) implied by transcriptomic analysis.

Authors: Miriam Hampel; Esteban Alonso; Irene Aparicio; James E Bron; Juan Luis Santos; John B Taggart; Michael J Leaver
Journal: Environ Sci Pollut Res Int Date: 2010-02-06 Impact factor: 4.223

10. Overexpression of Aldose Reductase Render Mouse Hepatocytes More Sensitive to Acetaminophen Induced Oxidative Stress and Cell Death.

Authors: Munzir M E Ahmed; J A S Al-Obosi; H M Osman; M E Shayoub
Journal: Indian J Clin Biochem Date: 2015-09-30

Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention.

1. Differential effects of acetaminophen on enzymatic and non-enzymatic antioxidant factors and plasma total antioxidant capacity in developing and adult rats.

2. Defensive nature of Sargassum polycystum (Brown alga) against acetaminophen-induced toxic hepatitis in rats: role of drug metabolizing microsomal enzyme system, tumor necrosis factor-alpha and fate of liver cell structural integrity.

3. Protective effect of Premna tomentosa extract (L. verbanacae) on acetaminophen-induced mitochondrial dysfunction in rats.

4. Mice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicity.

5. Potential physiological effects of pharmaceutical compounds in Atlantic salmon (Salmo salar) implied by transcriptomic analysis.

6. Proceedings of the British Pharmacological Society. Clinical Pharmacology Section. 14-16 April 1993. Abstracts.

7. Inhibition of mitochondrial respiration in vivo is an early event in acetaminophen-induced hepatotoxicity.

8. Comparative impacts of knockouts of two antioxidant enzymes on acetaminophen-induced hepatotoxicity in mice.

9. Abrogation by Trifolium alexandrinum root extract on hepatotoxicity induced by acetaminophen in rats.

10. Overexpression of Aldose Reductase Render Mouse Hepatocytes More Sensitive to Acetaminophen Induced Oxidative Stress and Cell Death.