Literature DB >> 16283437

Loss of 22q chromosome is related to glioma progression and loss of 10q.

Florence Laigle-Donadey1, Emmanuelle Crinière, Alexandra Benouaich, Emmanuelle Lesueur, Karima Mokhtari, Khe Hoang-Xuan, Marc Sanson.   

Abstract

Loss of heterozygosity (LOH) of chromosome 22q has been investigated in 160 gliomas. LOH at one or more microsatellite increased with increasing grade of the tumor (P < 0.01). LOH22q was more frequent in astrocytic tumors (37%) compared to mixed or oligodendroglial tumors (21%) (P = 0.02). LOH22q was correlated to 10q loss but not to 1p or 9p loss. Taken together, these data suggest that LOH22q is an alteration associated with malignant progression of gliomas.

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Year:  2006        PMID： 16283437     DOI： 10.1007/s11060-005-7019-2

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  14 in total

1.  A region of common deletion in 22q13.3 in human glioma associated with astrocytoma progression.

Authors:  N T Oskam; E H Bijleveld; T J Hulsebos
Journal:  Int J Cancer       Date:  2000-02-01       Impact factor: 7.396

2.  Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations.

Authors:  N Sévenet; A Lellouch-Tubiana; D Schofield; K Hoang-Xuan; M Gessler; D Birnbaum; C Jeanpierre; A Jouvet; O Delattre
Journal:  Hum Mol Genet       Date:  1999-12       Impact factor: 6.150

3.  Frequent LOH on 22q12.3 and TIMP-3 inactivation occur in the progression to secondary glioblastomas.

Authors:  Mitsutoshi Nakamura; Eiwa Ishida; Keiji Shimada; Munehiro Kishi; Hiroyuki Nakase; Toshisuke Sakaki; Noboru Konishi
Journal:  Lab Invest       Date:  2005-02       Impact factor: 5.662

4.  Common regions of deletion on chromosome 22q12.3-q13.1 and 22q13.2 in human astrocytomas appear related to malignancy grade.

Authors:  Y Ino; J S Silver; L Blazejewski; R Nishikawa; M Matsutani; A von Deimling; D N Louis
Journal:  J Neuropathol Exp Neurol       Date:  1999-08       Impact factor: 3.685

5.  Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas.

Authors:  C Ebert; M von Haken; B Meyer-Puttlitz; O D Wiestler; G Reifenberger; T Pietsch; A von Deimling
Journal:  Am J Pathol       Date:  1999-08       Impact factor: 4.307

6.  Analysis of the NF2 gene in oligodendrogliomas and ependymomas.

Authors:  M Eva Alonso; M Josefa Bello; Dolores Arjona; Pilar Gonzalez-Gomez; Jesus Lomas; Jose M de Campos; M Elena Kusak; Alberto Isla; Juan A Rey
Journal:  Cancer Genet Cytogenet       Date:  2002-04-01

Review 7.  Molecular changes in gliomas.

Authors:  Marc Sanson; Joëlle Thillet; Khê Hoang-Xuan
Journal:  Curr Opin Oncol       Date:  2004-11       Impact factor: 3.645

8.  MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer.

Authors:  Michiho Nishioka; Takashi Kohno; Masachika Tani; Nozomu Yanaihara; Yoshio Tomizawa; Ayaka Otsuka; Shigeru Sasaki; Keiko Kobayashi; Toshiro Niki; Arafumi Maeshima; Yoshitaka Sekido; John D Minna; Saburo Sone; Jun Yokota
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-03       Impact factor: 11.205

9.  Fine mapping of chromosome 22q tumor suppressor gene candidate regions in astrocytoma.

Authors:  Christian Hartmann; Astrid Nümann; Wolf Mueller; Nikola Holtkamp; Matthias Simon; Andreas von Deimling
Journal:  Int J Cancer       Date:  2004-03-01       Impact factor: 7.396

10.  Analysis of the NF2 tumor-suppressor gene and of chromosome 22 deletions in gliomas.

Authors:  K Hoang-Xuan; P Merel; F Vega; J P Hugot; P Cornu; J Y Delattre; M Poisson; G Thomas; O Delattre
Journal:  Int J Cancer       Date:  1995-02-08       Impact factor: 7.396
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  4 in total

1.  A preliminary study of apoptosis induction in glioma cells via alteration of the Bax/Bcl-2-p53 axis by transformed and non-transformed root extracts of Leonurus sibiricus L.

Authors:  Przemysław Sitarek; Ewa Skała; Monika Toma; Marzena Wielanek; Janusz Szemraj; Malgorzata Nieborowska-Skorska; Maciej Kolasa; Tomasz Skorski; Halina Wysokińska; Tomasz Śliwiński
Journal:  Tumour Biol       Date:  2016-01-07

2.  The Influence of Gene Aberrations on Survival in Resected IDH Wildtype Glioblastoma Patients: A Single-Institution Study.

Authors:  Ondrej Kalita; Zuzana Sporikova; Marian Hajduch; Magdalena Megova Houdova; Rastislav Slavkovsky; Lumir Hrabalek; Matej Halaj; Yvona Klementova; Martin Dolezel; Jiri Drabek; Lucie Tuckova; Jiri Ehrmann; Jana Vrbkova; Radek Trojanec; Miroslav Vaverka
Journal:  Curr Oncol       Date:  2021-03-21       Impact factor: 3.677

3.  Sequential filtering for clinically relevant variants as a method for clinical interpretation of whole exome sequencing findings in glioma.

Authors:  Ege Ülgen; Özge Can; Kaya Bilguvar; Cemaliye Akyerli Boylu; Şirin Kılıçturgay Yüksel; Ayça Erşen Danyeli; O Uğur Sezerman; M Cengiz Yakıcıer; M Necmettin Pamir; Koray Özduman
Journal:  BMC Med Genomics       Date:  2021-02-23       Impact factor: 3.063

4.  Tumor Heterogeneity and Molecular Characteristics of Glioblastoma Revealed by Single-Cell RNA-Seq Data Analysis.

Authors:  Dhanusha Yesudhas; S Akila Parvathy Dharshini; Y-H Taguchi; M Michael Gromiha
Journal:  Genes (Basel)       Date:  2022-02-25       Impact factor: 4.096
  4 in total

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