OBJECTIVE: We sought to determine whether women with ovarian cancer have increased occupational exposure to triazine herbicides. METHODS: A population-based case-control study of incident cases (n=256) and random digit-dialed control subjects (n=1122) was conducted. Participants were administered telephone interviews to obtain agricultural work history. These histories were used with the statewide pesticide usage database to calculate cumulative exposure estimates. The data were analyzed by stratified analysis and unconditional logistic regression techniques. RESULTS: The analysis of ever versus never occupational exposure to triazines demonstrated that cases were slightly but not significantly more likely to be exposed than control subjects (adjusted odds=1.34; 95% confidence interval=0.77-2.33). There was no evidence of a dose-response relationship between triazines and ovarian cancer (P=0.22). CONCLUSIONS: Considered with previous studies and animal laboratory data, the current evidence is not persuasive as to the presence or absence of an association between ovarian cancer and triazine exposure.
OBJECTIVE: We sought to determine whether women with ovarian cancer have increased occupational exposure to triazine herbicides. METHODS: A population-based case-control study of incident cases (n=256) and random digit-dialed control subjects (n=1122) was conducted. Participants were administered telephone interviews to obtain agricultural work history. These histories were used with the statewide pesticide usage database to calculate cumulative exposure estimates. The data were analyzed by stratified analysis and unconditional logistic regression techniques. RESULTS: The analysis of ever versus never occupational exposure to triazines demonstrated that cases were slightly but not significantly more likely to be exposed than control subjects (adjusted odds=1.34; 95% confidence interval=0.77-2.33). There was no evidence of a dose-response relationship between triazines and ovarian cancer (P=0.22). CONCLUSIONS: Considered with previous studies and animal laboratory data, the current evidence is not persuasive as to the presence or absence of an association between ovarian cancer and triazine exposure.
Authors: Jessica L Rinsky; Claudia Hopenhayn; Vijay Golla; Steve Browning; Heather M Bush Journal: Public Health Rep Date: 2012 Jan-Feb Impact factor: 2.792
Authors: Stella Koutros; Michael C R Alavanja; Jay H Lubin; Dale P Sandler; Jane A Hoppin; Charles F Lynch; Charles Knott; Aaron Blair; Laura E Beane Freeman Journal: J Occup Environ Med Date: 2010-11 Impact factor: 2.162
Authors: Maki Inoue-Choi; Peter J Weyer; Rena R Jones; Benjamin J Booth; Kenneth P Cantor; Kim Robien; Mary H Ward Journal: Occup Environ Med Date: 2016-07-01 Impact factor: 4.402
Authors: A C Gore; V A Chappell; S E Fenton; J A Flaws; A Nadal; G S Prins; J Toppari; R T Zoeller Journal: Endocr Rev Date: 2015-11-06 Impact factor: 19.871
Authors: Laura E Beane Freeman; Jennifer A Rusiecki; Jane A Hoppin; Jay H Lubin; Stella Koutros; Gabriella Andreotti; Shelia Hoar Zahm; Cynthia J Hines; Joseph B Coble; Francesco Barone-Adesi; Jennifer Sloan; Dale P Sandler; Aaron Blair; Michael C R Alavanja Journal: Environ Health Perspect Date: 2011-05-27 Impact factor: 9.031
Authors: Soo Lim; Sun Young Ahn; In Chan Song; Myung Hee Chung; Hak Chul Jang; Kyong Soo Park; Ki-Up Lee; Youngmi Kim Pak; Hong Kyu Lee Journal: PLoS One Date: 2009-04-13 Impact factor: 3.240