Literature DB >> 16282869

Associations between submicrometer particles exposures and blood pressure and heart rate in patients with lung function impairments.

Kai-Jen Chuang1, Chang-Chuan Chan, Guang-Ming Shiao, Ta-Chen Su.   

Abstract

OBJECTIVE: The objective of this study was to evaluate whether submicrometer particle is associated with elevated blood pressure (BP) and heart rate (HR).
METHODS: We measured ambulatory systolic BP (SBP), diastolic BP (DBP), and HR using a portable BP monitoring system and number concentrations of submicrometer particle with a size range of 0.02 to 1 microm (NC0.02-1) by a P-TRAK Ultrafine Particle Counter for 10 patients with lung function impairments.
RESULTS: We found NC0.02-1 exposures at 1- to 3-hour moving averages were associated with the elevation of SBP, DBP, and HR. There were 1.4 to 3.4-mm-Hg increases in SBP, 1.4 to 2.2-mm-Hg increases in DBP, and 0.3 to 3.5-beats/min increases in HR for 10,000 particles/cm increases in NC0.02-1 at 1- to 3-hour moving averages.
CONCLUSIONS: Exposures to submicrometer particles were associated with short-term increases in BP and HR in patients with lung function impairments.

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Year:  2005        PMID: 16282869     DOI: 10.1097/01.jom.0000181749.03652.f9

Source DB:  PubMed          Journal:  J Occup Environ Med        ISSN: 1076-2752            Impact factor:   2.162


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