Literature DB >> 16277332

A linchpin approach to unsaturated fatty acids: 11,12-epoxyeicosatrienoic acid and 11S,12S-dihydroxyeicosatrienoic acid ethyl esters.

Douglass F Taber1, Zhe Zhang.   

Abstract

[Chemical reaction: See text] A "linchpin" coupling strategy is described for the construction of long-chain fatty acid metabolites. This strategy led to a short synthesis of the ethyl esters of both 11,12-epoxyeicosatrienoic acid (EET) and 11S,12S-dihydroxyeicosatrienoic acid (DHET).

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Year:  2005        PMID： 16277332     DOI： 10.1021/jo0512094

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  1 in total

1.  First Total Synthesis of the Potent Anticancer Natural Product Dideoxypetrosynol A: Preparation of the "Skipped" (Z)-Enediyne Moiety by Oxidative Coupling of Homopropargyl Phosphonium Ylide.

Authors:  Benjamin W Gung; Ann O Omollo
Journal:  European J Org Chem       Date:  2008-08-21
  1 in total

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