Literature DB >> 1627650

The cDNA cloning and mRNA expression of rat protein C.

T Okafuji1, K Maekawa, K Nawa, Y Marumoto.   

Abstract

We cloned a cDNA coding for rat protein C, which provides hybridization probes for the detection of protein C mRNA in several tissues. The cloned cDNA was 1543 bp long and contained a single open reading frame of 1383 nucleotides. The proposed rat protein C precursor contained 461 amino acid residues: a 41 amino acid preproleader sequence, and light (155 amino acids) and heavy (263 amino acids) chains joined by a Lys-Arg dipeptide. Northern blot analysis showed that the rat protein C mRNA was expressed not only in the liver, but also in the kidney.

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Year:  1992        PMID: 1627650     DOI: 10.1016/0167-4781(92)90035-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  2 in total

1.  A novel missense mutation (Thr176-->Ile) at the putative hinge of the neo N-terminus of activated protein C.

Authors:  P J Hallam; A I Wacey; P M Mannucci; C Legnani; W Kühnau; M Krawczak; V V Kakkar; D N Cooper
Journal:  Hum Genet       Date:  1995-04       Impact factor: 4.132

2.  Extrahepatic expression and regulation of protein C in the mouse.

Authors:  K Yamamoto; D J Loskutoff
Journal:  Am J Pathol       Date:  1998-08       Impact factor: 4.307

  2 in total

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