Literature DB >> 16276015

Surgical management of skin cancers: experience from a regional cancer centre in North India.

S V Deo1, Sidhartha Hazarika, Nootan K Shukla, Sunil Kumar, Madhabananda Kar, Atul Samaiya.   

Abstract

AIMS: To review the disease profile and treatment outcome of patients with primary skin malignancies treated at a regional cancer centre. SETTINGS AND
DESIGN: Surgical oncology unit of a tertiary care regional cancer centre. Evaluation of treatment outcome of patients with skin cancer from Surgical Oncology database was done.
MATERIALS AND METHODS: Retrospective analysis of records of 77 patients with skin cancers treated between 1995 and 2002 was conducted. Profile of patients with skin cancer, surgical details including the management of primary tumour, regional lymph nodes and reconstructive procedures performed and survivals were analysed. STATISTICAL ANALYSIS: All computations were done using the Statistical Package for Social Sciences (SPSS-9). Descriptive statistics were calculated in a standard fashion and survival analysis was performed using Kaplan-Meier method.
RESULTS: Skin cancers constituted 2.4% (77/3154) of patients with cancer treated in the surgical oncology department. Squamous cell carcinoma (SCC) was the most common histological type (55.8%) followed by melanoma (26.1%) and basal cell carcinoma (BCC, 18.1%). Forty one percent of patients had undergone some form of intervention elsewhere before being referred. Reconstruction was required in 55.8% patients with large postresection defects. Regional lymph nodal dissection was required in 32.4% of total patients. Five-year median disease-free survival for the entire study population was 75%.
CONCLUSIONS: Skin cancers constitute a small but significant proportion of patients with cancer. Unlike in the Western countries, SCC is the commonest histologic variety. Primary level inadequate intervention is very common. Optimal results can be obtained with radical surgery and optimal surgical margins along with a reconstructive procedure when needed.

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Year:  2005        PMID: 16276015     DOI: 10.4103/0019-509x.17059

Source DB:  PubMed          Journal:  Indian J Cancer        ISSN: 0019-509X            Impact factor:   1.224


  11 in total

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5.  A child with xeroderma pigmentosum for excision of basal cell carcinoma.

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8.  The analysis of reasons for malignant skin tumors late diagnosis.

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10.  Histomorphologic Profile of Skin Tumors.

Authors:  Rupendra Thapa; Pranita Gurung; Suspana Hirachand; Sanju Babu Shrestha
Journal:  JNMA J Nepal Med Assoc       Date:  2018 Nov-Dec       Impact factor: 0.406

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