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Literature DB >> 16275950

Immunoglobulin G kappa [IgG kappa] and IgG lambda paraproteinemia in a child with AIDS and response to highly active antiretroviral therapy.

Filiz Odabasi Seeborg¹, Hannah Gay, Lorenz M Schmiege, David Bernard, William T Shearer.

Abstract

We report an 8-year-old boy with AIDS, extremely elevated serum immunoglobulin G (IgG) concentration and IgG kappa [IgG(kappa)] and IgG lambda [IgG(lambda)] paraproteinemia. This paraproteinemia partially responded to highly active antiretroviral therapy. This case emphasizes the importance of controlling B-cell activation.

Entities: Disease Species

Mesh：

Substances：

Year: 2005 PMID： 16275950 PMCID： PMC1287768 DOI： 10.1128/CDLI.12.11.1331-1333.2005

Source DB: PubMed Journal: Clin Diagn Lab Immunol ISSN： 1071-412X

16 in total

1. Potent antiretroviral therapy initiates normalization of hypergammaglobulinemia and a decline in HIV type 1-specific antibody responses.

Authors: D W Notermans; J J de Jong; J Goudsmit; M Bakker; M T Roos; L Nijholt; J Cremers; J A Hellings; S A Danner; A de Ronde
Journal: AIDS Res Hum Retroviruses Date: 2001-07-20 Impact factor: 2.205

1. Case report of peritoneal carcinomatosis of plasma cell origin in a patient with newly diagnosed HIV: A terminal event.

Authors: Syeda Sahra; Abdullah Jahangir; Muhammad Yasir Anwar; Allison Glaser; Ahmad Jahangir
Journal: AIDS Res Ther Date: 2021-07-19 Impact factor: 2.250

1 in total

Immunoglobulin G kappa [IgG kappa] and IgG lambda paraproteinemia in a child with AIDS and response to highly active antiretroviral therapy.

1. Potent antiretroviral therapy initiates normalization of hypergammaglobulinemia and a decline in HIV type 1-specific antibody responses.

Review 2. B-cell activation and HIV-1 infection: deeds and misdeeds.

3. [Paraproteins and lymphoma in HIV positive patients].

4. Oligoclonal immunoglobulins in the sera of healthy subjects at risk for AIDS.

5. Triclonal gammopathy in a patient with AIDS.

6. Brief report: myeloma-associated paraprotein directed against the HIV-1 p24 antigen in an HIV-1-seropositive patient.

7. IgG oligoclonal bands in sera of HIV-1 infected patients are mainly directed against HIV-1 determinants.

Review 8. Paraproteinemia, plasmacytoma, myeloma and HIV infection.

9. Plasma cell hyperplasia and monoclonal paraproteinemia in human immunodeficiency virus-infected patients.

10. Paraproteinemia in patients with acquired immunodeficiency syndrome (AIDS) or lymphadenopathy syndrome (LAS).

1. Case report of peritoneal carcinomatosis of plasma cell origin in a patient with newly diagnosed HIV: A terminal event.