Literature DB >> 1627536

Detailed mapping of the Rfv-1 gene that influences spontaneous recovery from Friend retrovirus-induced leukaemia.

M Miyazawa1, J Nishio, K Wehrly, G Jay, R W Melvold, B Chesebro.   

Abstract

Using H-2 recombinant and mutant mice, the Rfv-1 gene influencing spontaneous recovery from Friend retrovirus (FV)-induced leukaemia was mapped in the D locus. Two Db alleles were required for full recovery, and a single Dd transgene did not convey increased susceptibility to FV in the presence of homozygous Db/b genotype. The results suggest that an increase in the expression of Db may lead to more effective stimulation of FV-specific CTL.

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Year:  1992        PMID： 1627536     DOI： 10.1111/j.1744-313x.1992.tb00054.x

Source DB:  PubMed          Journal:  Eur J Immunogenet        ISSN： 0960-7420


  6 in total

Review 1.  Immunity to retroviral infection: the Friend virus model.

Authors:  K J Hasenkrug; B Chesebro
Journal:  Proc Natl Acad Sci U S A       Date:  1997-07-22       Impact factor: 11.205

2.  Role of natural killer cells in resistance against friend retrovirus-induced leukemia.

Authors:  N Iwanami; A Niwa; Y Yasutomi; N Tabata; M Miyazawa
Journal:  J Virol       Date:  2001-04       Impact factor: 5.103

3.  Major histocompatibility complex class I gene controls the generation of gamma interferon-producing CD4(+) and CD8(+) T cells important for recovery from friend retrovirus-induced leukemia.

Authors:  K E Peterson; M Iwashiro; K J Hasenkrug; B Chesebro
Journal:  J Virol       Date:  2000-06       Impact factor: 5.103

4.  Contrasting effects from a single major histocompatibility complex class II molecule (H-2E) in recovery from Friend virus leukemia.

Authors:  L L Perry; M Miyazawa; K Hasenkrug; K Wehrly; C S David; B Chesebro
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

5.  Novel role of CD8(+) T cells and major histocompatibility complex class I genes in the generation of protective CD4(+) Th1 responses during retrovirus infection in mice.

Authors:  Karin E Peterson; Ingunn Stromnes; Ron Messer; Kim Hasenkrug; Bruce Chesebro
Journal:  J Virol       Date:  2002-08       Impact factor: 5.103

6.  Recovery from Friend disease in mice with reduced major histocompatibility complex class I expression.

Authors:  K J Hasenkrug; G J Sprangrude; J Nishio; D M Brooks; B Chesebro
Journal:  J Virol       Date:  1994-04       Impact factor: 5.103
  6 in total

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