Literature DB >> 16275355

In vitro cleavage of Nedd8 from cullin 1 by COP9 signalosome and deneddylase 1.

Kosj Yamoah1, Kenneth Wu, Zhen-Qiang Pan.   

Abstract

Enzymatic cleavage of Nedd8 from its cullin conjugates plays a critical role in ubiquitin-dependent proteolysis by regulating the activity of the cullin-based RING-H2 E3 ubiquitin ligases. This chapter provides methods for the preparation of two Nedd8 isopeptidases: the COP9 signalosome and human deneddylase 1. It also describes the development of cell-free systems for cleavage of the Nedd8-cullin 1 isopeptide bond formed in vitro or in vivo.

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Year:  2005        PMID： 16275355     DOI： 10.1016/S0076-6879(05)98042-7

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  9 in total

1.  CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.

Authors:  Shih-Ching Lo; Mark Hannink
Journal:  Mol Cell Biol       Date:  2006-02       Impact factor: 4.272

2.  Expression, purification and crystallization of a PCI domain from the COP9 signalosome subunit 7 (CSN7).

Authors:  Moshe Dessau; Daniel A Chamovitz; Joel A Hirsch
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-10-20

Review 3.  Function and regulation of protein neddylation. 'Protein modifications: beyond the usual suspects' review series.

Authors:  Gwénaël Rabut; Matthias Peter
Journal:  EMBO Rep       Date:  2008-09-19       Impact factor: 8.807

4.  Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system.

Authors:  Rajesh K Singh; Sylvia Zerath; Oded Kleifeld; Martin Scheffner; Michael H Glickman; David Fushman
Journal:  Mol Cell Proteomics       Date:  2012-10-26       Impact factor: 5.911

5.  The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy.

Authors:  Teresa A Soucy; Lawrence R Dick; Peter G Smith; Michael A Milhollen; James E Brownell
Journal:  Genes Cancer       Date:  2010-07

6.  Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry.

Authors:  Lei Fang; Xiaorong Wang; Kosj Yamoah; Phang-lang Chen; Zhen-Qiang Pan; Lan Huang
Journal:  J Proteome Res       Date:  2008-10-14       Impact factor: 4.466

7.  Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species.

Authors:  Amrita Kumar; Huixia Wu; Lauren S Collier-Hyams; Jason M Hansen; Tengguo Li; Kosj Yamoah; Zhen-Qiang Pan; Dean P Jones; Andrew S Neish
Journal:  EMBO J       Date:  2007-10-04       Impact factor: 11.598

8.  IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.

Authors:  Jingzi Zhang; Ruoyu Zhao; Clinton Yu; Christine L N Bryant; Kenneth Wu; Zhihong Liu; Yibing Ding; Yue Zhao; Bin Xue; Zhen-Qiang Pan; Chaojun Li; Lan Huang; Lei Fang
Journal:  J Proteome Res       Date:  2020-02-03       Impact factor: 4.466

9.  Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism.

Authors:  Ethan D Emberley; Ruzbeh Mosadeghi; Raymond J Deshaies
Journal:  J Biol Chem       Date:  2012-07-05       Impact factor: 5.157
  9 in total

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