Use of a hierarchical logistic regression model to determine the impact of war injuries on clinical pregnancy rates in patients undergoing intracytoplasmic sperm injection.

OBJECTIVE: To determine the effects of war injuries, including spinal cord injuries, poisoning, and other injuries, on clinical pregnancy rates in infertile couples undergoing intracytoplasmic sperm injection (ICSI) and to compare the results with infertile couples who were not victims of the war.
DESIGN: Retrospective study.
SETTING: A large, national clinic in Tehran, Iran. PATIENT(S): Six hundred sixty-seven couples undergoing ICSI. INTERVENTION(S): Database analysis. MAIN OUTCOME MEASURE(S): Ongoing clinical pregnancy. RESULT(S): War victims with spinal cord injuries and those who had been poisoned had the same pregnancy rates as did infertile couples who were not victims of the war. The predictive model shows that the more embryos that are transferred, the more the chances for clinical pregnancies; in addition, the more cycles a couple undergoes, the fewer are the chances for clinical pregnancy in an additional cycle. Finally, younger females have more chances for clinical pregnancy than do older ones. CONCLUSION(S): Intracytoplasmic sperm injection is an appropriate option for the treatment of infertile war victim couples, especially for couples suffering from spinal cord injuries and poisoning.