Literature DB >> 1627248

Does the HIV envelope induce a chronic graft-versus-host-like disease?

J Habeshaw1, E Hounsell, A Dalgleish.   

Abstract

Evidence is accumulating that susceptibility to disease following HIV infection is genetically restricted. In addition, activation of the immune response appears to play an important role in disease progression. Here, John Habeshaw and colleagues propose that HIV envelope glycoproteins mimic foreign MHC molecules and, in doing so, stimulate alloreactive lymphocytes. This activation may explain the marked clinical and immunological similarities between chronic GVHD and AIDS.

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Year:  1992        PMID： 1627248     DOI： 10.1016/0167-5699(92)90155-Z

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  12 in total

1.  A gp120 HIV peptide with high similarity to HLA class II beta chains enhances PPD-specific and autoreactive T cell activation.

Authors:  O Pugliese; M Viora; B Camponeschi; P Cordiali Fei; F Caprilli; A Chersi; M Evangelista; A M Di Massimo; V Colizzi
Journal:  Clin Exp Immunol       Date:  1992-11       Impact factor: 4.330

2.  Phenotypes of mononuclear cell infiltrates in human central nervous system.

Authors:  Y Iwasaki; K Sako; I Tsunoda; Y Ohara
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

3.  Diversity and virulence thresholds in AIDS.

Authors:  R J de Boer; M C Boerlijst
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

4.  HIV induces deletion of T cell receptor variable gene product-specific T cells.

Authors:  A S Bansal; L M Green; S H Khoo; R S Pumphrey; M R Haeney; B K Mandal
Journal:  Clin Exp Immunol       Date:  1993-10       Impact factor: 4.330

5.  Prior mucosal exposure to heterologous cells alters the pathogenesis of cell-associated mucosal feline immunodeficiency virus challenge.

Authors:  Surender B Kumar; Sarah Leavell; Kyle Porter; Barnabe D Assogba; Mary J Burkhard
Journal:  Retrovirology       Date:  2010-05-28       Impact factor: 4.602

6.  Suppressed cellular alloimmune responses in HIV-exposed seronegative female sex workers.

Authors:  W Jennes; D Evertse; M-Y Borget; B Vuylsteke; C Maurice; J N Nkengasong; L Kestens
Journal:  Clin Exp Immunol       Date:  2006-03       Impact factor: 4.330

7.  An octapeptide analogue of HIV gp120 modulates protein tyrosine kinase activity in activated peripheral blood T lymphocytes.

Authors:  D J Phipps; P Reed-Doob; D K MacFadden; J P Piovesan; G B Mills; D R Branch
Journal:  Clin Exp Immunol       Date:  1995-06       Impact factor: 4.330

8.  Cross-linking of Fas by antibodies to a peculiar domain of gp120 V3 loop can enhance T cell apoptosis in HIV-1-infected patients.

Authors:  F Silvestris; S Nagata; P Cafforio; N Silvestris; F Dammacco
Journal:  J Exp Med       Date:  1996-12-01       Impact factor: 14.307

9.  Recognition of HIV-1 peptides by host CTL is related to HIV-1 similarity to human proteins.

Authors:  Morgane Rolland; David C Nickle; Wenjie Deng; Nicole Frahm; Christian Brander; Gerald H Learn; David Heckerman; Nebosja Jojic; Vladimir Jojic; Bruce D Walker; James I Mullins
Journal:  PLoS One       Date:  2007-09-05       Impact factor: 3.240

10.  Conversion of an immunogenic human immunodeficiency virus (HIV) envelope synthetic peptide to a tolerogen in chimpanzees by the fusogenic domain of HIV gp41 envelope protein.

Authors:  B F Haynes; L O Arthur; P Frost; T J Matthews; A J Langlois; T J Palker; M K Hart; R M Scearce; D M Jones; C McDanal
Journal:  J Exp Med       Date:  1993-03-01       Impact factor: 14.307
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