Literature DB >> 1627247

HIV interactions with CD4: a continuum of conformations and consequences.

L E Eiden1, J D Lifson.   

Abstract

Here, Lee Eiden and Jeffrey Lifson present a model for HIV envelope glycoprotein-CD4 interactions that attempts to reconcile recent, seemingly conflicting, structural, biochemical and biological observations. Central to this model is the involvement of both the CDR2-like and CDR3-like domains of CD4 in the interaction with gp120, leading to a conformational change and dissociation of gp120 from the gp120-gp41 complex.

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Year:  1992        PMID： 1627247     DOI： 10.1016/0167-5699(92)90154-Y

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  22 in total

1.  Inhibition of HIV-1-mediated syncytium formation and virus replication by the lipophosphoglycan from Leishmania donovani is due to an effect on early events in the virus life cycle.

Authors:  N Genois; B Barbeau; M Olivier; M J Tremblay
Journal:  Clin Exp Immunol       Date:  2001-04       Impact factor: 4.330

2.  Isolation and partial characterization of ovine lentivirus in Czech Republic.

Authors:  V Celer; H Nĕmcová; V Celer
Journal:  Folia Microbiol (Praha)       Date:  1997       Impact factor: 2.099

3.  Postbinding events mediated by human immunodeficiency virus type 1 are sensitive to modifications in the D4-transmembrane linker region of CD4.

Authors:  S Moir; J Perreault; L Poulin
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

4.  Concordant modulation of neutralization resistance and high infectivity of the primary human immunodeficiency virus type 1 MN strain and definition of a potential gp41 binding site in gp120.

Authors:  Maria Leavitt; Eun Ju Park; Igor A Sidorov; Dimiter S Dimitrov; Gerald V Quinnan
Journal:  J Virol       Date:  2003-01       Impact factor: 5.103

5.  Biological and pharmacokinetic properties of a novel immunoglobulin-CD4 fusion protein.

Authors:  J B Lyczak; S L Morrison
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574

6.  Sodium lauryl sulfate abrogates human immunodeficiency virus infectivity by affecting viral attachment.

Authors:  J Bestman-Smith; J Piret; A Désormeaux; M J Tremblay; R F Omar; M G Bergeron
Journal:  Antimicrob Agents Chemother       Date:  2001-08       Impact factor: 5.191

7.  Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction.

Authors:  H J Ryser; E M Levy; R Mandel; G J DiSciullo
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205

Review 8.  The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.

Authors:  S Bour; R Geleziunas; M A Wainberg
Journal:  Microbiol Rev       Date:  1995-03

9.  A monoclonal antibody to the CDR-3 region of CD4 inhibits soluble CD4 binding to virions of human immunodeficiency virus type 1.

Authors:  J P Moore
Journal:  J Virol       Date:  1993-06       Impact factor: 5.103

10.  Human immunodeficiency virus type 1 envelope glycoprotein molecules containing membrane fusion-impairing mutations in the V3 region efficiently undergo soluble CD4-stimulated gp120 release.

Authors:  E A Berger; J R Sisler; P L Earl
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103
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