OBJECTIVE: We examined the relationship between migraines and preeclampsia risk. STUDY DESIGN: Cases were 244 women with preeclampsia and controls were 470 normotensive women. Women were asked if a physician had ever told them that they had migraines. Odds ratios (OR) and 95% confidence intervals (CI) were calculated. RESULTS: A history of migraines was associated with a 1.8-fold increased risk of preeclampsia (95% CI 1.1-2.7). Women who were 30+ years old when diagnosed with migraines had the highest risk (OR 2.8, 95% CI 0.8-9.0). The migraine-preeclampsia association appeared to be modified by pre-pregnancy overweight status (p = 0.06). Overweight migrainous women, compared with lean nonmigrainous women, had a 12-fold increased preeclampsia risk (95% CI 5.9-25.7). CONCLUSION: Our findings are consistent with reports from six of eight previous studies on the topic. Nevertheless, prospective cohort studies are needed to further evaluate the extent to which migraines and/or its treatments are associated with preeclampsia risk.
OBJECTIVE: We examined the relationship between migraines and preeclampsia risk. STUDY DESIGN: Cases were 244 women with preeclampsia and controls were 470 normotensive women. Women were asked if a physician had ever told them that they had migraines. Odds ratios (OR) and 95% confidence intervals (CI) were calculated. RESULTS: A history of migraines was associated with a 1.8-fold increased risk of preeclampsia (95% CI 1.1-2.7). Women who were 30+ years old when diagnosed with migraines had the highest risk (OR 2.8, 95% CI 0.8-9.0). The migraine-preeclampsia association appeared to be modified by pre-pregnancy overweight status (p = 0.06). Overweight migrainouswomen, compared with lean nonmigrainous women, had a 12-fold increased preeclampsia risk (95% CI 5.9-25.7). CONCLUSION: Our findings are consistent with reports from six of eight previous studies on the topic. Nevertheless, prospective cohort studies are needed to further evaluate the extent to which migraines and/or its treatments are associated with preeclampsia risk.
Authors: Michelle A Williams; B Lee Peterlin; Bizu Gelaye; Daniel A Enquobahrie; Raymond S Miller; Sheena K Aurora Journal: Headache Date: 2011-07-28 Impact factor: 5.887
Authors: Sixto E Sanchez; Michelle A Williams; Percy N Pacora; Cande V Ananth; Chungfang Qiu; Sheena K Aurora; Tanya K Sorensen Journal: BMC Womens Health Date: 2010-10-26 Impact factor: 2.809