| Literature DB >> 16271861 |
Amy L Brittle1, Hiroyuki Ohkura.
Abstract
The centrosome is the main microtubule organising centre in the cell. During mitosis, centrosomes dramatically increase microtubule nucleating activity, enabling them to form a mitotic spindle. Recent studies show that Aurora A kinase promotes microtubule assembly from centrosomes through the phosphorylation of the conserved centrosomal protein TACC.Mesh：
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Year: 2005 PMID： 16271861 DOI： 10.1016/j.cub.2005.10.022
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834