| Literature DB >> 16271756 |
Keith K Wannomae1, Steven D Christensen, Andrew A Freiberg, Shayan Bhattacharyya, William H Harris, Orhun Kamil Muratoglu.
Abstract
Irradiation decreases the wear of ultra-high molecular weight polyethylene (UHMWPE) but generates residual free radicals, precursors to long-term oxidation. Melting or annealing is used in quenching free radicals. We hypothesized that irradiated and once-annealed UHMWPE would oxidize while irradiated and melted UHMWPE would not, and that the oxidation in the former would increase wear. Acetabular liners were real-time aged by immersion in an aqueous environment that closely mimicked the temperature and oxygen concentration of synovial fluid. After 95 weeks of real-time aging, once-annealed components were oxidized; the melted components were not. The wear rate of the real-time aged irradiated and once-annealed components was higher than the literature reported values of other contemporary highly cross-linked UHMWPEs. Single annealing after irradiation used with terminal gamma sterilization may adversely affect the long-term oxidative stability of UHMWPE components.Entities:
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Year: 2005 PMID： 16271756 DOI： 10.1016/j.biomaterials.2005.10.002
Source DB: PubMed Journal: Biomaterials ISSN： 0142-9612 Impact factor: 12.479