Pin Dong1, Jie Wang, Bin Jin, Qiang Wang, Guo-liang Wang, Xin-wei Chen. 1. Department of Otorhinolaryngology Head and Neck Surgery,Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China. dongpin64@yahoo.com.cn
Abstract
OBJECTIVE: To evaluate the results of surgery for laryngeal carcinoma. METHODS: A retrospective analysis of long-term therapeutic effect was made on surgery of 105 patients with laryngeal carcinoma in the past 15 years. There were 197 males, 8 cases of female. Tumor stage were included 3 cases of Tis NOMO, 45 cases of T1NOM0, 1 case of T1N1M0, 88 cases of T2NOM0, 3 cases of T2N1M0, 1 case of T2N2M0, 33 cases of T3NOM0, 7 cases of T3N1M0, 3 cases of T3N2M0, 13 cases of T4NOM0, 6 cases of T4N1M0, 1 case of T4N2M0 and 1 case of T4N3M0. Different kinds of operations were as follows: cordectomy (1 case) or stripping (2 cases) by suspended laryngoscope, laryngofissure (9 cases), vertical partial laryngectomy without tracheotomy (16 cases), vertical partial laryngectomy (25 cases), horizontal laryngectomy (7 cases), Arslan's procedure (15 cases), cricohyoidoepiglottopexy (57 cases), subtotal laryngectomy (16 cases) and total laryngectomy (57 cases). RESULTS: There were only four missing cases among all 205 cases. The 3- and 5-year survival rate for glatt and carcinoma is 91.3% and 84. 7% respectively. The 3- and 5-year survival rate for supraglottic carcinoma is 67.5% and 65.0% respectively. Statistical differences were noted between survival rate of glottic and supraglottic carcinoma and between early and advantage disease. The overall 3- and 5-year survival rate is 84.8% and 79.4% respectively. The rate of surgical preservation of laryngeal function is 72.7%. CONCLUSIONS: The prognosis factors of laryngeal cancer were tumor stage, subsite, neck metastasis. All patients treated with different surgical techniques had fairly good quality of functional results. It is possible to preserve the laryngeal function by proper indication, safe margin, combined radiotherapy without compromising survival.
OBJECTIVE: To evaluate the results of surgery for laryngeal carcinoma. METHODS: A retrospective analysis of long-term therapeutic effect was made on surgery of 105 patients with laryngeal carcinoma in the past 15 years. There were 197 males, 8 cases of female. Tumor stage were included 3 cases of Tis NOMO, 45 cases of T1NOM0, 1 case of T1N1M0, 88 cases of T2NOM0, 3 cases of T2N1M0, 1 case of T2N2M0, 33 cases of T3NOM0, 7 cases of T3N1M0, 3 cases of T3N2M0, 13 cases of T4NOM0, 6 cases of T4N1M0, 1 case of T4N2M0 and 1 case of T4N3M0. Different kinds of operations were as follows: cordectomy (1 case) or stripping (2 cases) by suspended laryngoscope, laryngofissure (9 cases), vertical partial laryngectomy without tracheotomy (16 cases), vertical partial laryngectomy (25 cases), horizontal laryngectomy (7 cases), Arslan's procedure (15 cases), cricohyoidoepiglottopexy (57 cases), subtotal laryngectomy (16 cases) and total laryngectomy (57 cases). RESULTS: There were only four missing cases among all 205 cases. The 3- and 5-year survival rate for glatt and carcinoma is 91.3% and 84. 7% respectively. The 3- and 5-year survival rate for supraglottic carcinoma is 67.5% and 65.0% respectively. Statistical differences were noted between survival rate of glottic and supraglottic carcinoma and between early and advantage disease. The overall 3- and 5-year survival rate is 84.8% and 79.4% respectively. The rate of surgical preservation of laryngeal function is 72.7%. CONCLUSIONS: The prognosis factors of laryngeal cancer were tumor stage, subsite, neck metastasis. All patients treated with different surgical techniques had fairly good quality of functional results. It is possible to preserve the laryngeal function by proper indication, safe margin, combined radiotherapy without compromising survival.