Literature DB >> 16270389

Mesenchymal hamartoma of liver: magnetic resonance imaging and histopathologic correlation.

Bin-Bin Ye1, Bing Hu, Li-Jun Wang, Hong-Sheng Liu, Yan Zou, Yu-Bin Zhou, Zhuang Kang.   

Abstract

AIM: To describe the imaging features of hepatic mesenchymal hamartoma with emphasis on magnetic resonance imaging (MRI) compared to histopathologic results.
METHODS: Spin-echo sequence(SE),fast spin-echo sequence(FSE) were performed in 12 children (7 males,5 females) with mesenchymal hamartoma of the liver (MHL), aged 1.2 months to 12 years;( mean age, 6.3 years) axial, saggital, coronary plain imaging with an Elscint 2.0T MR equipment. Their main symptoms were abdominal mass (5 cases), enlarged liver (8 cases), abdominal pain (1 case) and anemia (2 cases), and negative alphafetoprotein. Dynamic enhancement examination was added in 2 cases.
RESULTS: Six cases had single mass type of MHL, in which 3 cases had solid masses showing slight low-signal-intensity in T1WI, and irregular high-signal-intensity in T2WI, 1 case had a cystic-solid mixed mass showing several border-clear cysts in a solid mass, 2 cases had cystic masses with multi-septa. Five cases had diffuse and multifocal lesions type of MHL with its signal intensity being similar to that of the solid mass. One case had a combined diffuse and single cystic mass. In the early dynamic enhancement examination, the lesions were slightly circum-enhanced , and the center was enhanced in the later scan images. Inner hepatic vessels were compressed in 5 cases, vena cava and abdominal aortae were compressed in 3 cases. Pathological findings included fiber hyperplasia, hyaline degeneration, biliary duct hyperplasia, lobule-like array.
CONCLUSION: MR imaging is a better way to differentiate and diagnose MHL. MHL may be recognized by its characteristic occurrence in infancy and MR imaging features.

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Year:  2005        PMID: 16270389      PMCID: PMC4479680          DOI: 10.3748/wjg.v11.i37.5807

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  13 in total

1.  Mesenchymal hamartoma of the liver.

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2.  Myoid hamartoma of the liver--a novel variant of hamartoma developing in the hilar region and imitating a malignant liver tumor.

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Journal:  Med Sci Monit       Date:  2004-06-01

Review 3.  Malignant transformation of mesenchymal hamartoma of the liver: case report and review of the literature.

Authors:  T M Ramanujam; J C Ramesh; D W Goh; K T Wong; W A Ariffin; G Kumar; N A Taib
Journal:  J Pediatr Surg       Date:  1999-11       Impact factor: 2.545

Review 4.  Fetal mesenchymal hamartoma of the liver: report of a case.

Authors:  Shinkichi Kamata; Keisuke Nose; Toshio Sawai; Toshimichi Hasegawa; Seika Kuroda; Takashi Sasaki; Akira Okada; Masahiro Tawara
Journal:  J Pediatr Surg       Date:  2003-04       Impact factor: 2.545

Review 5.  Benign tumors of the liver.

Authors:  E M Brunt
Journal:  Clin Liver Dis       Date:  2001-02       Impact factor: 6.126

6.  Mesenchymal hamartoma of the liver. A 35-year review.

Authors:  C A DeMaioribus; K P Lally; K Sim; H Isaacs; G H Mahour
Journal:  Arch Surg       Date:  1990-05

7.  Third report of t(19q)(13.4) in mesenchymal hamartoma of liver with comments on link to embryonal sarcoma.

Authors:  K E Bove; R I Blough; S Soukup
Journal:  Pediatr Dev Pathol       Date:  1998 Sep-Oct

8.  Mesenchymal hamartoma of the liver: radiologic-pathologic correlation.

Authors:  P R Ros; Z D Goodman; K G Ishak; A H Dachman; W W Olmsted; D S Hartman; J E Lichtenstein
Journal:  Radiology       Date:  1986-03       Impact factor: 11.105

9.  Mesenchymal hamartoma of the liver. DNA flow cytometric analysis of eight cases.

Authors:  T M Otal; J B Hendricks; P Pharis; W H Donnelly
Journal:  Cancer       Date:  1994-08-15       Impact factor: 6.860

10.  Pediatric hepatic mesenchymal hamartoma demonstrated on plain film, ultrasound and MRI, and correlated with pathology.

Authors:  M H Wholey; K J Wojno
Journal:  Pediatr Radiol       Date:  1994
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  4 in total

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Authors:  Debraj Sen; Y S Gulati; Anusree Majumder; Saikat Bhattacharjee; Ritwik Chakrabarti
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2.  Mesenchymal cystic hamartoma of the liver: MR imaging with pathologic correlation.

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Journal:  J Radiol Case Rep       Date:  2009-07-01

Review 3.  Assessment of malignant liver tumors in children.

Authors:  Derek J Roebuck
Journal:  Cancer Imaging       Date:  2009-10-02       Impact factor: 3.909

4.  Hepatic von Meyenburg complex: a trigger of severe portal hypertension.

Authors:  Shuhei Yoshida; Kazutaka Kurokohchi; Takuya Ueno; Morihiko Yoshino; Masahiko Shimada; Tsutomu Masaki
Journal:  Liver Int       Date:  2008-10-14       Impact factor: 5.828

  4 in total

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