Literature DB >> 16268652

Highly regioselective synthesis of 1-aryl-3 (or 5)-alkyl/aryl-5 (or 3)-(N-cycloamino)pyrazoles.

S Peruncheralathan1, A K Yadav, H Ila, H Junjappa.   

Abstract

[Reaction: see text]. An efficient highly regioselective protocol for the synthesis of isomeric 1,3-diaryl (or 1-aryl-3-alkyl) and 1,5-diaryl (or 1-aryl-5-alkyl)-5 (or 3)-(N-cycloamino)pyrazoles has been reported by cyclocondensation of common alpha-oxoketene N,S-acetal precursors with arylhydrazines by variation of reaction conditions.

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Year:  2005        PMID： 16268652     DOI： 10.1021/jo051478u

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

1.  Synthesis of diverse N-acyl-pyrazoles via cyclocondensation of hydrazides with α-oxeketene dithioacetal.

Authors:  Bruna Á Pereira; Alcione V de Bastos; Wystan K O Teixeira; Sidnei Moura E Silva; Alex F C Flores; Darlene C Flores
Journal:  Mol Divers       Date:  2017-08-08       Impact factor: 2.943

2.  (E)-6-(4-Chloro-phen-yl)-4-[(2-cyano-3-phenyl-all-yl)sulfan-yl]-2,2-difluoro-3-phenyl-1,3,2-oxaza-borinin-3-ium-2-uide.

Authors:  Ming Li; Shu-Wen Wang; Li-Rong Wen
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-04-05

3.  Synthesis of Some New 3, 5-Bis (substituted) Pyrazoles and Isoxazoles Based on (N'(1)E, N'(3)E)- N'(1), N'(3)-Bis (3, 4, 5-substitutedbenzlidene) Malonohydrazide under Solvothermal Conditions.

Authors:  Ebraheem Abdu Musad; Kuriya Madavu Lokanatha Rai; Kullaiah Byrappa
Journal:  Int J Biomed Sci       Date:  2010-03

4.  Studies with beta-oxoalkanonitriles: simple novel synthesis of 3-[2,6-diaryl-4- pyridyl]-3-oxopropanenitriles.

Authors:  Sayed M Riyadh; Hamad M Al-Matar; Mohamed H Elnagdi
Journal:  Molecules       Date:  2008-12-15       Impact factor: 4.411

5.  Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies.

Authors:  Candice Soares de Melo; Vinayak Singh; Alissa Myrick; Sandile B Simelane; Dale Taylor; Christel Brunschwig; Nina Lawrence; Dirk Schnappinger; Curtis A Engelhart; Anuradha Kumar; Tanya Parish; Qin Su; Timothy G Myers; Helena I M Boshoff; Clifton E Barry; Frederick A Sirgel; Paul D van Helden; Kirsteen I Buchanan; Tracy Bayliss; Simon R Green; Peter C Ray; Paul G Wyatt; Gregory S Basarab; Charles J Eyermann; Kelly Chibale; Sandeep R Ghorpade
Journal:  J Med Chem       Date:  2021-01-04       Impact factor: 7.446
  5 in total

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